Results 41 to 50 of about 3,437 (296)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

A Compact Dual-band Antenna Based on Defected Ground Structure for ISM Band Applications

open access: yes, 2020
This paper presents the design and realization of a compact dual-band antenna for industrial scientific and medical (ISM) band applications. The compact geometry of the antenna is achieved by combining two miniaturization techniques like defected ground ...
Hussain, N, Awan, WA, Ghaffar, A, Li, XJ
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Miniaturized microstrip antenna array using defected ground structure with enhanced performance

open access: yesEngineering Science and Technology, an International Journal, 2016
The aim of this work is to obtain a miniaturized microstrip patch antenna array using defected ground structure (DGS) for S band at 2.2 GHz. Initially the patch antenna array designed at C band resonates at 5.2 GHz.
Rashmi A. Pandhare   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Bandwidth Optimization of a Textile PIFA with DGS Using Characteristic Mode Analysis

open access: yesSensors, 2021
This work presents the design and optimization of an antenna with defected ground structure (DGS) using characteristic mode analysis (CMA) to enhance bandwidth.
Bashar Bahaa Qas Elias   +4 more
doaj   +1 more source

Coplanar waveguide with defected ground structure for nanosecond subcellular electroporation

open access: yes, 2011
Compact measurement setup and test structure for nanosecond electroporation of biological cells were demonstrated. The test structure was based on a coplanar waveguide with a defected ground structure that afforded broadband impedance match with little ...
S. Halder   +10 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Planar fractal filter on defected ground substrate

open access: yes, 2012
The diploma thesis is focused on the design of planar filters combining fractal layouts and defected ground substrates. The diploma thesis can be divided into three main parts.
Kufa, Martin
core   +1 more source

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