Results 161 to 170 of about 169,080 (262)

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung   +19 more
wiley   +1 more source

HIV-1 virome profiling using HIV-PULSE to guide therapeutic and curative interventions. [PDF]

open access: yesEBioMedicine
De Braekeleer S   +15 more
europepmc   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

open access: yesAdvanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du   +4 more
wiley   +1 more source

Lifetime Estimation of Defective Products from the Imaginal Mixture of Defective and Non-defective Products: The Trunsored Data Model

open access: yesLifetime Estimation of Defective Products from the Imaginal Mixture of Defective and Non-defective Products: The Trunsored Data Model
In solving the lifetime estimation problem of defective products using samples of size N from a mixture of defective and non-defective products, a new method of estimating the parameters of the underlying distribution function is proposed. We suppose that the ratio of the defective products to the non-defective products is unknown.
openaire  

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

open access: yesAdvanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi   +3 more
wiley   +1 more source

Persistence of proinsulin-only secretion in people with long-duration diabetes and minimal residual insulin secretion. [PDF]

open access: yesDiabet Med
Metghalchi S   +11 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy