Results 31 to 40 of about 14,834 (217)
Motivated by a risk process with positive and negative premium rates, we consider a real-valued Markov additive process with finitely many background states.
Miyazawa, Masakiyo
core +2 more sources
Probabilistic description of the first-order Fermi acceleration in shock waves: Time-dependent solution by single-particle approach [PDF]
We give a new coherent description of the first-order Fermi acceleration of particles in shock waves from the point of view of stochastic process of the individual particles, under the test particle approximation.
Kato, Tsunehiko N., Takahara, Fumio
core +3 more sources
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou +8 more
wiley +1 more source
AI in chemical engineering: From promise to practice
Abstract Artificial intelligence (AI) in chemical engineering has moved from promise to practice: physics‐aware (gray‐box) models are gaining traction, reinforcement learning complements model predictive control (MPC), and generative AI powers documentation, digitization, and safety workflows.
Jia Wei Chew +4 more
wiley +1 more source
Structural basis for DNMT3A-mediated de novo DNA methylation. [PDF]
DNA methylation by de novo DNA methyltransferases 3A (DNMT3A) and 3B (DNMT3B) at cytosines is essential for genome regulation and development. Dysregulation of this process is implicated in various diseases, notably cancer.
Chen, Dongliang +11 more
core +2 more sources
‘Turkeys Cannot Vote for Christmas’: Why Epistemic Disobedience in an Anti‐Black World Matters
ABSTRACT Never in the history of global coloniality has the idea of epistemic disobedience been as important as in the 21st century. This is not only because the struggle for decolonisation has shifted from physical confrontation between the coloniser and the colonised into a battle of ideas but also because the former has deployed the idea of ...
Morgan Ndlovu
wiley +1 more source
ABSTRACT The Carnac alignments in Morbihan (France) are among the most famous Neolithic sites of the world. Paradoxically, they have benefited little from a thorough renewal of archaeological data over the past century. There are many reasons for this, but it is mainly because the site has been regarded more as a monument to visit and protect than as ...
Guillaume Bruniaux +6 more
wiley +1 more source
Density and Distribution Evaluation for Convolution of Independent Gamma Variables
Several numerical evaluations of the density and distribution of convolution of independent gamma variables are compared in their accuracy and speed. In application to renewal processes, an efficient formula is derived for the probability mass function ...
Hu, Chaoran +2 more
core +1 more source
Objective Complement component 4 (C4), encoded by C4A and C4B within the major histocompatibility complex (MHC) on chromosome 6, regulates the immune response and clears immune complexes. The variable copy number (CN) of C4 genes and retroviral human endogenous retrovirus K (HERV‐K) element influence its function.
Javier Martínez‐López +156 more
wiley +1 more source

