Results 61 to 70 of about 1,550,828 (242)

Operating in perpetual motion? Coping with the dark side of global boundary spanning

open access: yesGlobal Strategy Journal, EarlyView.
Abstract Research Summary This paper explores how individuals experience and cope with the demands of global boundary spanning in multinational enterprises (MNEs). We foreground temporary colocation as a modality through which mobile global boundary spanners repeatedly traverse multiple boundaries, triggering intense demands with adverse consequences ...
Kieran M. Conroy   +2 more
wiley   +1 more source

Booklet, Urban Renewal Land, 1966

open access: yes, 1966
A booklet on property development opportunities in downtown Tampa and the riverfront due to the Urban Renewal Program.https://digitalcommons.usf.edu/pizzo_records/1005/thumbnail ...
Tampa (Fla.). Urban Renewal Agency
core  

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

open access: yesiMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo   +4 more
wiley   +1 more source

Multi‐omics–driven precision medicine

open access: yesiMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li   +20 more
wiley   +1 more source

Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells

open access: yesInterdisciplinary Medicine, EarlyView.
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen   +6 more
wiley   +1 more source

Democracy Renewal

open access: yes, 2015
Democracy Renewal brings together diverse opinions, analysis and statistics from academics, leaders, journalists and citizens from around the world on the state of contemporary liberal democracy.
Melbourne School of Government
core  

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli   +5 more
wiley   +1 more source

The Differing Phenotypes of the Three Most Common Postsynaptic Congenital Myasthenic Syndromes Governed by Their Underlying Molecular Pathogenic Mechanisms

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT The congenital myasthenic syndromes are rare disorders of impaired signal transmission at the neuromuscular junction. Despite next generation sequencing facilitating the identification of variants in myasthenic‐associated genes, these variants are frequently of unknown significance and the clinical diagnosis can be delayed.
David Beeson
wiley   +1 more source

Repeated Pleistocene Permafrost Episodes in the Western Pannonian Basin

open access: yesPermafrost and Periglacial Processes, EarlyView.
ABSTRACT Concerning the study of past periglacial processes, the Pannonian Basin is a key area as it contains the southernmost frost polygons found in Central Europe. The presence or absence of permafrost is still, however, a matter of debate, and data on the timing of frost action are also scarce.
Krisztina Sebe   +5 more
wiley   +1 more source

How do Market Concentration and Mimetic Behavior Influence Strategic Renewal? [PDF]

open access: yes
In the increasingly dynamic and competitive business environment of today, incumbent firms are facing rapid and profound changes in macro social, economic, political and technological conditions.
Vasile DEAC   +1 more
core  

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