Results 61 to 70 of about 120,521 (347)

The procedure of solving complaints at the Ministry of internal affairs [PDF]

open access: yesGlasnik Advokatske komore Vojvodine, 2015
During the performance of increasingly complex and demanding security tasks, police enforce various powers in different environments and is influenced by many factors, which facilitate or hinder their implementation. Powers are exclusively established to
Bikarević Darko
doaj  

Defending the gut [PDF]

open access: yesNature Reviews Neuroscience, 2019
Gut-innervating sensory neurons drive host defensive responses against Salmonella infection in mice.
openaire   +2 more sources

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Algorithm for introducing the appointed defense lawyer into the criminal process: how to avoid a “double defense” situation [PDF]

open access: yesПенитенциарная наука
Introduction: the right to receive qualified legal assistance is enshrined in Article 48 of the Constitution of the Russian Federation. It is the right of everyone who is subject to criminal prosecution, regardless of the financial situation of the ...
Konin V.V.
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Defendant-sided unjust factors [PDF]

open access: yes, 2016
This paper will examine the structure of the defendant-sided unjust factors, by which I mean duress and undue influence. The paper first argues that undue influence is based on abuse of deferential trust placed in the defendant and duress on an ...
Sheehan, Duncan, Sheehan, D
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Who defends the defenders?

open access: yes
Environmental and human rights defenders are vital in addressing ecosystem degradation and climate change. Operating on the frontlines in areas under pressure from legal and illegal forces, they mobilize communities to resist environmental harm and social injustices.
Risso, Melina   +3 more
openaire   +2 more sources

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