Results 31 to 40 of about 769,770 (306)

The Ascent to Manufacturing Competitiveness: Defense Firms vs. Non-Defense Firm [PDF]

, 2003
Facing rapidly changing markets and increasing competition, the competitive environment of the defense industry has undergone extensive restructuring, significantly more so than for the non-defense sector.
Noble, Margaret A.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

What Impedes Universities from Creating Dual-Purpose Technologies?

Foresight and STI Governance, 2017
Modern universities play a significant role, and in some countries, a key role, in research and development on a large variety of topics, often belonging to the sphere of national security.
Mikhail Kuzyk, Anna Grebenyuk, Evgenia Kakaeva, Evgeniy Manchenko, Vladimir Dovgiy   +4 more
doaj   +1 more source

PORTER’S DIAMOND MODEL AND THE COMPETITIVENESS OF THE TURKISH DEFENSE INDUSTRY [PDF]

Journal of Defense Resources Management, 2021
Turkish Defense Industry is the locomotive of the national technology move. However, there is a need to develop strategies in line with the national strategic objectives to increase the contribution of the defense industry to the national competitive ...
Göksel KORKMAZ, Mustafa Kemal TOPCU
doaj  

Analysis of cybersecurity threats in Industry 4.0: the case of intrusion detection [PDF]

, 2018
Nowadays, industrial control systems are experiencing a new revolution with the interconnection of the operational equipment with the Internet, and the introduction of cutting-edge technologies such as Cloud Computing or Big data within the organization.
A Moreno, AW Colombo, C McParland, GM Upadhyay, IM Khalil, J Dean, K Zhang, M Brettel, M Chiang, S Wang, T Stock, W Dazhong, X Xu   +12 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

An Initial Look at Technology and Institutions on Defense Industry Consolidation [PDF]

, 2004
Conventional wisdom holds that defense industry consolidation resulted from decreased defense spending. However, we maintain that understanding dynamic changes in key defense institutions helps provide a more complete explanation for observed ...
Driessnack, John D., King, David R.
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The Military Influence on Industrial Policies in Brazil During the 20th and Early 21st Centuries

Brasiliana: Journal for Brazilian Studies, 2022
The defense industry is a part of a country’s industrial base and often has multiple uses, serving both civilian and military purposes. It does not stand alone and is a significant part of the country’s industry.
Vitelio Brustolin
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source