Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling
Advanced Healthcare Materials, EarlyView.Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian +10 more
wiley +1 more source
The Defense Mechanism of PpCAD4 in <i>Physcomitrium patens</i> Against <i>Botrytis cinerea</i>. [PDF]
Plants (Basel)Wu M +7 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Deployable medical devices typically need external stimuli to trigger deployment. However, external stimuli are difficult to supply within tissues. Here, we describe a strategy to deploy small‐scale structures into soft tissues after insertion without the need for any stimulus. We demonstrate deployment within a tissue phantom.
Yeh‐Chia Tseng +13 more
wiley +1 more source
An efficient three-tier defense mechanism for mitigation of DDoS attack with port connection analysis in SDN. [PDF]
Sci RepRajper A +5 more
europepmc +1 more source
The Contradiction of Self-Perception and Defense Mechanisms in a Sample of Infertile Women
Aseel Al-Shami, Rami Tashtoush
openalex +1 more source
Advanced Healthcare Materials, EarlyView.Ionizable lipid nanoparticles target multiple pathological pathways in neurodegeneration. The designed self‐assembled materials undergo a pH‐triggered structural transformation from a cubosome/hexosome coexistence to a hexosome phase, enhancing intracellular delivery of a multi‐target phytochemical formulation. The antioxidant‐loaded pH‐responsive LNPs
Thelma Akanchise +4 more
wiley +1 more source
Extracellular traps, an ancient defense mechanism described in hemocytes of the tick Rhipicephalus microplus. [PDF]
Parasit VectorsAguilar-Díaz H +7 more
europepmc +1 more source
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Advanced Healthcare Materials, EarlyView.Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Heat shock factor regulation of antimicrobial peptides expression suggests a conserved defense mechanism induced by febrile temperature in arthropods. [PDF]
ElifeXiao B +5 more
europepmc +1 more source
Chemical exposure and alveolar macrophages responses: 'the role of pulmonary defense mechanism in inhalation injuries'. [PDF]
BMJ Open Respir Res, 2023 Tapak M +3 more
europepmc +1 more source