Results 111 to 120 of about 9,269,203 (381)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

An SDN-based Approach For Defending Against Reflective DDoS Attacks

, 2018
Distributed Reflective Denial of Service (DRDoS) attacks are an immanent threat to Internet services. The potential scale of such attacks became apparent in March 2018 when a memcached-based attack peaked at 1.7 Tbps.
Erb, Benjamin, Kargl, Frank, Kleber, Stephan, Lukaseder, Thomas, Stölzle, Kevin   +4 more
core   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Overexpression of OsPGIP2 confers Sclerotinia sclerotiorum resistance in Brassica napus through increased activation of defense mechanisms

Journal of Experimental Botany, 2018
Overexpression of rice OsPGIP2 in Brassica napus results in resistance to Sclerotinia sclerotiorum by increasing activation of defense mechanisms and inhibiting fungal SsPG3 and SsPG6 proteins.
Zhuanrong Wang, L. Wan, Qiang Xin, Ye Chen, Xiaohui Zhang, Faming Dong, Dengfeng Hong, Guangsheng Yang   +7 more
semanticscholar   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Psychological Defense Mechanisms and Alexithymia in Cancer Patients

Bihdād, 2018
Introduction: The goal of this research was to compare Alexithymia and psychological defense mechanisms in cancer patients with normal group. Also, investigation of the predictive role of three defense mechanisms in Alexithymia was considered.
Seyed Reza SeyedTabaee, Parvin Rahmatinejad, Seyed Davood Mohammadi, Seyed Davood Mohammadi, Valiollah Akbari   +4 more
doaj  

Clinical applications of the Defense Mechanisms Rating Scale-Self-Report-30: a systematic review of the first five years

Research in Psychotherapy
Defense mechanisms are automatic psychological processes that regulate emotional conflicts and modulate adaptation to internal and external stressors.
Gabriella Martino, Orlando Silvestro, Emanuele M. Merlo, Carmelo M. Vicario, Alessandro Meduri, Gianluca Lo Coco   +5 more
doaj   +1 more source

DEFENSE STYLE MECHANISM OF THE STUDENTS (AZEIRBAIJAN CASE)

, 2022
G. Aliyeva
openalex   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source