Results 171 to 180 of about 44,641 (272)
Ordinary defensive medicine: in the shadows of general practitioners' postures toward (over-)medicalisation. [PDF]
Philos Ethics Humanit MedCordey M +4 more
europepmc +1 more source
Triple‐Mode Ferroelectric Thin‐Film Transistor for Hybrid Electrical–Optical Reservoir Computing
Advanced Science, EarlyView.A triple‐mode ferroelectric thin‐film transistor is developed by integrating Si3N4/HZO/IGZO layers to realize three independent memory modes: electric long‐term, electric short‐term, and optical short‐term. This single‐device architecture functions as both a reservoir and readout layer, achieving 92.43% MNIST accuracy. It offers a fully hardware‐based,
Hyeonho Lee +9 more
wiley +1 more source
Policy Options for Reducing Defensive Medicine Behaviors: A Multi-Method Study. [PDF]
Med J Islam Repub IranZarei E +5 more
europepmc +1 more source
Do Doctors Practice Defensive Medicine?
'Defensive medicine' is a potentially serious social problem: if fear of liability drives health care providers to administer treatments that do not have worthwhile medical benefits, then the current liability system may generate inefficiencies much ...
McClellan, Mark, Kessler, Daniel
core
Advanced Science, EarlyView.Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin +12 more
wiley +1 more source
A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance
Advanced Science, EarlyView.A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang +9 more
wiley +1 more source
Factors associated with defensive medicine practice in United Arab Emirates: A cross-sectional study with multivariate analysis. [PDF]
Medicine (Baltimore)Al Awar S, Sallam G, Elbiss H.
europepmc +1 more source
Advanced Science, EarlyView.This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang +10 more
wiley +1 more source
Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy
Advanced Science, EarlyView.MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang +11 more
wiley +1 more source