Results 51 to 60 of about 44,641 (272)
Eurasian Journal of MedicineBackground: The fear of malpractice is a significant factor influencing physicians’ decision-making processes in modern medical practice. This can cause defensive medicine, which involves behaviors such as requesting unnecessary tests and imaging ...
Kamber Kasali +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
A Survey On Frequency Of Defensive Medicine Among General Practitioners Of Kerman City
پیاورد سلامت, 2014 Background and Aim: Defensive medicine is a potential social problem which can bring about consequences for public health regarding the quality of personal care and wastage of limited health resources.
Mohammadreza Amiresmaili +4 more
doaj +2 more sources
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Examining Defensive Medicine Behaviors in Physicians in Terms of Socio-Demographic Variables: A Cross-Sectional Study [PDF]
Introduction: The aim of this cross-sectional study is to evaluate physicians' attitudes regarding defensive medicine practices and to investigate defensive medicine practices in terms of socio-demographic variables.
Karasu, Emre
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
The Professional Medical Journal, 2014 Objective: To determine the prevalence of defensive medicine among doctors of Civil Hospital and Jinnah Hospital Karachi and to introduce it towards the community of doctors. Material And Methods: 200 doctors from different wards of Civil Hospital Karachi and Jinnah Hospital Karachi played crucial role in filling of Performa which was especially ...
Fahad Khan +5 more
openaire +2 more sources
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source