Results 81 to 90 of about 40,355 (239)

Defensive medicine [PDF]

open access: yesAnaesthesia, 1985
D.W. Bethune   +4 more
openaire   +3 more sources

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

open access: yesAdvanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj   +21 more
wiley   +1 more source

Adaptive 4D‐Printed Vascular Stents With Low‐Temperature‐Activated and Intelligent Deployment

open access: yesAdvanced Functional Materials, EarlyView.
Microarchitected coronary artery stents were fabricated using a polycaprolactone (PCL)‐based shape memory polymer (SMP) composite via projection micro‐stereolithography (PµSL) 4D printing. By incorporating diethyl phthalate (DEP) as a plasticizer, the thermal transition temperature (Ttran) was modulated to about 37°C, enabling rapid and autonomous ...
Yannan Li   +12 more
wiley   +1 more source

MPI‐Guided Photothermal Therapy of Prostate Cancer Using Stem Cell Delivery of Magnetotheranostic Nanoflowers

open access: yesAdvanced Functional Materials, EarlyView.
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi   +7 more
wiley   +1 more source

From In‐Silico Optimized Microfabrication to Experimental Validation: Engineering a Tridimensional Epi‐Intraneural Interface

open access: yesAdvanced Functional Materials, EarlyView.
An epi‐intraneural interface is developed through in silico optimization and a novel tridimensional microfabrication pipeline. The device integrates penetrating and epineural contacts on a flexible substrate. Mechanical, electrochemical, and in vivo testing in rat and pig reveal robust implantation, low‐threshold activation, and site‐dependent ...
Federico Ciotti   +14 more
wiley   +1 more source

Microneedle‐Based Biofertilizer Delivery Improves Plant Growth Through Microbiome Engineering

open access: yesAdvanced Functional Materials, EarlyView.
This figure shows how microneedles are used to deliver biofertilizers to enhance plant growth through microbial migration, metabolic reprogramming, and changes in plant endogenous microbiome. Abstract This study presents a microneedle‐based system for the delivery of rhizospheric biofertilizers into plant tissues to enhance growth.
Zhicheng Le   +14 more
wiley   +1 more source

Current status and solutions for the overuse of emergency CT in pediatric patients with abdominal pain

open access: yesFrontiers in Pediatrics
Pediatric abdominal pain is one of the most common issues reported in emergency departments (EDs), where emergency computed tomography (CT) plays a crucial role in diagnosing various conditions. However, the frequent use of emergency CT scans in children
Wei Weng, Yaomeng Chen
doaj   +1 more source

Biomimetic Ion‐Orchestrated Hierarchical Armored Hydrogel Coating for Robust and Multifunctional Surface Protection

open access: yesAdvanced Functional Materials, EarlyView.
Inspired by the skin‐toughening mechanism of marine sponges, an ion‐orchestrated structural engineering strategy is proposed to regulate the surface microstructure of hydrogel coatings, enabling the in situ formation of a robust armor layer that enhances mechanical integrity and provides multifunctional protection by suppressing fouling attachment and ...
Wenshuai Yang   +11 more
wiley   +1 more source

A Bioresorbable Neural Interface for On‐Demand Thermal Pain Block

open access: yesAdvanced Functional Materials, EarlyView.
Bioresorbable, implantable neural electronics provide dynamic, on‐demand thermal modulation of peripheral nerves for safe, drug‐free pain relief. A microscale thin‐film heater and temperature sensor embedded within biodegradable encapsulants enable precise temperature control via real‐time feedback.
Jeonghwan Park   +23 more
wiley   +1 more source

Home - About - Disclaimer - Privacy