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Spatial Structures; Movers and Shakers, Volume 2, Issue 1 [PDF]
, 2021 The Spatial Structures; Movers and Shakers e-magazine is part of aseries of activities in preparation for the Spatial Structures 2020/21conference, which will be held at the University of Surrey.In the spirit of the key theme of ‘Inspiring the next ...
Godina, Martha +1 more
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Arqueología de la Arquitectura, 2017 This paper contains part of the results gathered from the first architectonic study of the Castle of Leiria’s military structures, conducted within a master dissertation in Art History, from the University of Coimbra, combining Archaeology of ...
António Ginja
doaj +1 more source
Cerebellar contribution to the regulation of defensive states
Frontiers in Systems Neuroscience, 2023 Despite fine tuning voluntary movement as the most prominently studied function of the cerebellum, early human studies suggested cerebellar involvement emotion regulation.
Gabriela Neubert da Silva +3 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Functional organization of the midbrain periaqueductal gray for regulating aversive memory formation
Molecular Brain, 2021 Innately aversive experiences produce rapid defensive responses and powerful emotional memories. The midbrain periaqueductal gray (PAG) drives defensive behaviors through projections to brainstem motor control centers, but the PAG has also been ...
Li-Feng Yeh +2 more
doaj +1 more source
Drones, 2023 Digital recording of historic buildings and sites in mountainous areas could be challenging. The paper considers and discusses the case of historical defensive structures in the Italian Alps, designed and built to be not accessible.
Luigi Barazzetti +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source