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Long Term Deferiprone Chelation Therapy
2002A wide variety of compounds have been tested in animals and humans in order to find drugs which are capable of removing iron from patients with refractory anaemias receiving regular blood transfusions. Parenteral preparations which have been evaluated clinically include desferrioxamine (DFO), diethylene triamine penta-acetic acid (DTPA ...
Beatrix Wonke, Victor A. Hoffbrand
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Deferiprone approved for iron overload
American Journal of Health-System Pharmacy, 2011FDA on October 14 announced the approval of deferiprone oral tablets for the treatment of transfusional iron overload in patients with thalassemia whose previous chelation therapy did not produce an adequate response. The drug will be marketed as Ferriprox by ApoPharma Inc.
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The controversial role of deferiprone in the treatment of thalassemia
Journal of Laboratory and Clinical Medicine, 2001The role of the orally active iron (Fe) chelator deferiprone in the treatment of beta-thalassemia remains a controversial subject. Despite initial studies showing high Fe chelation efficacy in vitro and also in animals and human subjects, several latter studies have not been so successful.
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Fatal congestive heart failure with deferiprone
Gastroentérologie Clinique et Biologique, 2009V. Berdoukas, G. Chouliaras, V. Ladis
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PO017 Deferiprone is useful in blood
Leukemia Research, 2007M. Esposito +6 more
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