Bioinformatic Analysis and Molecular Docking Identify Isorhamnetin Is a Candidate Compound in the Treatment of Pulmonary Artery Hypertension. [PDF]
Shao C, Xia W, Liu Y.
europepmc +1 more source
Deficiency of Immunoglobulin A in Intestinal Disease
David M. Bull, Thomas B. Tomasi
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Germline variants in CDKN2A wild‐type melanoma prone families
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen+5 more
wiley +1 more source
Vitamin D deficiency and oral health: a systematic review of literature. [PDF]
Ziada S+3 more
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Globoid Cell Leucodystrophy (Krabbe's Disease): Deficiency of Galactocerebroside β-Galactosidase [PDF]
Kunihiko Suzuki, Yoshiyuki Suzuki
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Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Association of zinc deficiency and clinical symptoms, inflammatory markers, severity of COVID-19 in hospitalized children. [PDF]
Perestiuk V+3 more
europepmc +1 more source
Adenosine deaminase deficiency and severe combined immunodeficiency disease [PDF]
Martin B Van Der Weyden+1 more
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We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Oncostatin M silence and neopeptide: the value of exploring patients with rare inherited bone marrow failure. [PDF]
Delafontaine S, Meyts I.
europepmc +1 more source