Results 41 to 50 of about 1,781,024 (283)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Competitio, 2007 Tanulmányomban az Európai Unió egyik tagállamát, a korporatív gazdaság egyik példájának tekinthető Ausztria kis, nyitott, föderális berendezkedésű államát veszem górcső alá. Az osztrák gazdaságban a második világháború utáni újjáépítési periódust viharos
Kitti Vass
doaj +1 more source
Committees Tackle the Deficit [PDF]
, 2011 Summarizes the recommendations of a presidential commission and private bipartisan committee for reducing the federal deficit by cutting healthcare costs, Social Security outlays, and discretionary spending, and by raising ...
John L. Palmer, Rudolph G. Penner
core
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
THE CURRENT ACCOUNT OF ROMANIA EVOLUTION, FACTORS OF INFLUENCE, FINANCING [PDF]
Financial Studies, 2013 The balance of the current account is a tool used to establish the level of economic development of a country, its international specialization and its degree of dependence on foreign markets.
Camelia MILEA
doaj
State budget expenditures under martial law: Case of Ukraine [PDF]
Public and Municipal FinanceThe direction of the state budget to defense and the military-industrial complex under martial law imposes more stringent requirements on the system of formation and execution of state budget expenditures.
Igor Chugunov +5 more
doaj +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
COMPARABLE ANALYSIS REGARDING KEY MACROECONOMIC INDICATORS ON MOLDOVA’S WAY TOWARDS EUROPEAN INTEGRATION [PDF]
Economy and Sociology, 2015 As Moldova has the purpose to enter the European Union the actual situation in the country is analyzed in this article. The article gives the comparative analysis of the basic parameters of Moldova with the other European Union country-members to define ...
Valentina GANCIUCOV, Alina CEBAN
doaj
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source