Results 71 to 80 of about 2,578,764 (379)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

ANALYSIS OF INCOME AND EXPENDITURE BUDGET OF THE MUNICIPAL ADMINISTRATION TUKUY-MICHELSKEHO OF THE VILLAGE COUNCIL

Вестник Северо-Кавказского федерального университета, 2022
The local budget is the basis of each municipality, as to the adequacy or shortage of Finance affects the standard of living of the population and its social stability. In the article the definition of the local budget, revenues and expenditures, as well
Anna Savtsova, Olga Patsenko, Zukhra Yarykova   +2 more
doaj  

BAICE Thematic Forum:Challenging deficit discourses in international education and development [PDF]

, 2015
Research and policy in international education has o en been framed in terms of a deficit discourse. For instance, policy debates on women’s literacy and education have begun by positioning women as a group who need to ‘catch up’ on certain skills in ...
Aikman, Sheila, Dyer, Caroline, Rao, Nitya, Robinson-Pant, Anna, Rogers, Alan, Themelis, Spyros   +5 more
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

The Efficacy of Preventing Rachitis in Babies by Using Vitamin D Solutio Oleosa: the Results of a Short-Term Comparative Investigation

Педиатрическая фармакология, 2016
Background: Vitamin D-deficient states remain highly prevalent in children, according to Russian and foreign studies. Because of this, it is important to conduct timely prevention of rachitis in children, taking into account the commitment to therapy ...
T. V. Margieva, E. P. Zimina, E. A. Bakovich, S. G. Makarova, L. S. Namazova-Baranova, G. T. Yachyaeva, I. S. Kostyushina, O. V. Kojevnikova   +7 more
doaj   +1 more source

Deficit Reduction Through Diversity: How Affirmative Action at the FCC Increased Auction Competition [PDF]

In recent auctions for paging licenses, the Federal Communications Commission has granted businesses owned by minorities and women substantial bidding credits.
Ian Ayres, Peter Cramton
core  

A Frailty Index Based On Deficit Accumulation Quantifies Mortality Risk in Humans and in Mice

Scientific Reports, 2017
Although many common diseases occur mostly in old age, the impact of ageing itself on disease risk and expression often goes unevaluated. To consider the impact of ageing requires some useful means of measuring variability in health in animals of the ...
Kenneth Rockwood, Joanna M. Blodgett, O. Theou, M. Sun, H. Feridooni, A. Mitnitski, Robert A. Rose, Judith Godin, Edward Gregson, Susan E. Howlett   +9 more
semanticscholar   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

The Impact of Spinal Anesthesia and Use of Oxytocin on Fluid Absorption in Patients Undergoing Operative Hysteroscopy: Results from a Prospective Controlled Study

International Journal of Women's Health, 2020
Naser Al-Husban,1 Abdelkarim Aloweidi,2 Omar Ababneh2 1Obstetrics and Gynecology Department, School of Medicine, The University of Jordan, Amman, Jordan; 2Department of Anesthesia, School of Medicine, The University of Jordan, Amman, JordanCorrespondence:
Al-Husban N, Aloweidi A, Ababneh O
doaj