Results 71 to 80 of about 526,773 (268)
Early‐Phase Research in Pediatric Neuro‐Oncology
Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
FOREIGN EXPERIENCE AS SEEN THROUGH REFORMING PENSION SYSTEM IN RUSSIAN FEDERATION
Вестник Северо-Кавказского федерального университета, 2022 The item provides a view on the major issues in the pension system of Russia as well as some potential measures to overcome those in view of foreign experience.
Viktor T. Koibaev, Anna V. Savtsova
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Advantages of incorporating new varieties in the cultivation of cotton in the Sinú Valley
Temas Agrarios, 2018 The economic analysis of technological options is a complement to biophysical research. The objective of this work was to estimate the economic advantages of incorporating new varieties of cotton, to reduce the production ...
Antonio María Martinez Reina +4 more
doaj +1 more source
Turning round NHS deficits: Deficits are not for turning [PDF]
BMJ, 2006 EDITOR—Ham is right to be sceptical about the private turnaround teams.1 Personal experience with “franchising,” a similar process, has led me to a similar position.2 Faith in their abilities is misplaced for three reasons. Firstly, the private sector underestimates the wider responsibilities of hospitals.
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source
International transactions of the United States (1946-1968)
PSL Quarterly Review, 2014 In spite of the extensive literature on the deficit in the US balance of payments, there is a great deal of confusion on the subject. In the present article, the authors propose to concentrate on the presentation of the facts from 1946 to 1968 in a form ...
R. MOSSÉ
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source