Results 151 to 160 of about 37,807,015 (239)

The womb as the cradle of longevity: Perinatal origins of biological aging

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract The perinatal period is increasingly recognized as an important determinant of biological aging trajectories and disease susceptibility across the lifespan. This narrative review synthesizes current evidence linking intrauterine exposures to adult health outcomes across three biological dimensions: fetal programming, maternal influences, and ...
Sevim Ozge Ozdemir, Ebru Davutoglu
wiley   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Early Childhood Aggression in Autistic and Non-Autistic Preschoolers: Prevalence, Topography, and Relationship to Emotional Reactivity. [PDF]

open access: yesJAACAP Open
Sivathasan S   +6 more
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

open access: yesInterdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He   +3 more
wiley   +1 more source

Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells

open access: yesInterdisciplinary Medicine, EarlyView.
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen   +6 more
wiley   +1 more source

Engineered 3D cultured human nasal mucosa mesenchymal stem cell derived sEVs for targeted brain‐derived neurotrophic factor delivery to enhance neurogenesis and attenuate brain damage

open access: yesInterdisciplinary Medicine, EarlyView.
This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang   +13 more
wiley   +1 more source

Smart Sensor‐Integrated Lysimeter System for Affordable on‐Farm Crop Water Monitoring and Irrigation Management

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT Accurate monitoring of crop water use is critical for precision irrigation, yet conventional lysimeter systems remain too costly and complex for widespread adoption. This study presents the development and field validation of a low‐cost, information and communication technology (ICT)‐enabled weighing lysimeter system that integrates load cells,
Stephen Okwang, Younggu Her, Taeil Jang
wiley   +1 more source

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