Results 41 to 50 of about 842,357 (319)

Cognitive, Emotional, and Auto-Activation Dimensions of Apathy in Parkinson's Disease

Frontiers in Behavioral Neuroscience, 2017
Apathy is one of the most frequent non-motor manifestations in Parkinson's disease (PD) that can lead to a whole range of deleterious outcomes. In 2006, Levy and Dubois proposed a model that distinguishes three different apathy aetiologies in PD divided ...
Jonathan Del-Monte, Sophie Bayard, Pierluigi Graziani, Marie C. Gély-Nargeot   +3 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Growth and Weight Deficits in ADHD

Pediatric Neurology Briefs, 1996
The hypothesis that stimulant medications may cause growth deficits in children with attention deficit hyperactivity disorder (ADHD) was reevaluated in 124 children and adolescents with ADHD and 109 controls at the Massachusetts General Hospital, Boston,
J Gordon Millichap
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Attention deficits without cortical neuronal deficits [PDF]

Nature, 2012
The ability to process relevant stimuli selectively is a fundamental function of the primate visual system. The best-understood correlate of this function is the enhanced response of neurons in the visual cortex to attended stimuli. However, recent results show that the superior colliculus (SC), a midbrain structure, also has a crucial role in visual ...
Zénon, Alexandre, Krauzlis, Richard J.
openaire   +2 more sources

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Inconclusive evidence for associations between adverse experiences in adulthood and working memory performance

Royal Society Open Science
Decades of research have shown that adversity tends to be associated with lower working memory (WM) performance. This literature has mainly focused on impairments in the capacity to hold information available in WM for further processing.
Stefan Vermeent, Anna-Lena Schubert, Meriah L. DeJoseph, Jaap J. A. Denissen, Jean-Louis van Gelder, Willem E. Frankenhuis   +5 more
doaj   +1 more source

Postoperative cognitive deficits [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2006
Cognitive dysfunctions are relatively common in postoperative and critically ill patients. This complication not only compromises recovery after surgery, but, if persistent, it minimizes and compromises surgery itself.
Kalezić Nevena, Dimitrijević Ivan, Leposavić Ljubica, Kočica Mladen, Bumbaširević Vesna, Vučetić Čedomir, Paunović Ivan, Slavković Nemanja, Filimonović Jelena   +8 more
doaj   +1 more source

Disentangling Deficits in Adults With Attention-Deficit/Hyperactivity Disorder [PDF]

Archives of General Psychiatry, 2005
A lack of inhibitory control has been suggested to be the core deficit in attention-deficit/hyperactivity disorder (ADHD), especially in adults. This means that a primary deficit in inhibition mediates a cascade of secondary deficits in other executive functions, such as attention. Impaired stopping has been claimed to support the inhibition hypothesis.
Bekker, E.M., Overtoom, C.C.E., Kooij, J.J.S., Buitelaar, J.K., Verbaten, M.N., Kenemans, J.L.   +5 more
openaire   +6 more sources

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source