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Generalizing the Gaussian Network Model: Spanning‐Tree Thermodynamics Shows Entropy‐Driven KRAS Activation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The GTPase KRAS executes a conformational switch between a GTP‐bound active state and a GDP‐bound inactive state, a process central to oncogenic signaling. However, the structural basis of this switching at the level of residue‐contact organization remains incompletely characterized by traditional binary structural models.
Fatma Senguler Ciftci, Burak Erman
wiley +1 more source

Host gene expression analysis in the detection of bacterial and viral etiology in children hospitalized with a suspected severe infection. [PDF]

Commun Med (Lond)
Piri R +7 more
europepmc +1 more source

Phase I Multivariate Coefficient of Variation Control Charts for High‐Dimensional Processes

Quality and Reliability Engineering International, EarlyView.
ABSTRACT Multivariate control charts have traditionally focused on monitoring the process mean vector and/or covariance matrix. Recent studies have extended this framework to Phase II monitoring of the multivariate coefficient of variation (MCV); yet very limited work has examined MCV‐based monitoring in Phase I.
O. A. Oyegoke +2 more
wiley +1 more source

New Hidradenitis Suppurativa in Children: Influence of Neighborhood Socioeconomic Status. [PDF]

Pediatr Dermatol
Sanchez-Anguiano ME +6 more
europepmc +1 more source

Deep‐Learning Algorithm Diagnostic Support for Usual Interstitial Pneumonia Pattern Recognition in Fibrotic Interstitial Lung Disease

Respirology, EarlyView.
ABSTRACT Background and Objective High resolution computed tomography (HRCT) scan diagnostic classification for usual interstitial pneumonia (UIP) plays a critical role in therapeutic decision‐making and clinical trial eligibility for interstitial lung disease (ILD) patients, but is subject to variability.
Caitlin C. Fermoyle +313 more
wiley +1 more source

CT-Visible Venous Fat Embolus Associated With a Femoral Shaft Fracture in a Polytrauma Patient: A Case Report. [PDF]

Cureus
Choukri EM +4 more
europepmc +1 more source

Case Report: Negative initial endoscopy and 18F-FDG PET/CT may not exclude occult gastric cancer. [PDF]

Front Oncol
Jin Z +5 more
europepmc +1 more source

Optimal Homogeneous ℒp$$ {\boldsymbol{\mathcal{L}}}_{\boldsymbol{p}} $$‐Gain Controller

International Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT Nonlinear ℋ∞$$ {\mathscr{H}}_{\infty } $$‐controllers are designed for arbitrarily weighted, continuous homogeneous systems with a focus on systems affine in the control input. Based on the homogeneous ℒp$$ {\mathcal{L}}_p $$‐norm, the input–output behavior is quantified in terms of the homogeneous ℒp$$ {\mathcal{L}}_p $$‐gain as a ...
Daipeng Zhang +3 more
wiley +1 more source

Elevated Interleukin-6 Levels in Socioeconomically Disadvantaged Children With Borderline Subclinical Rheumatic Heart Disease in São Paulo, Brazil: A Prospective Cohort Study Highlighting Early Detection and Treatment Opportunities. [PDF]

J Am Heart Assoc
de Barros Branco CE +15 more
europepmc +1 more source

Optimal Gain Selection for the Arbitrary‐Order Homogeneous Differentiator

International Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT Differentiation of noisy signals is a relevant and challenging task. Widespread approaches are the linear high‐gain observer acting as a differentiator and Levant's robust exact differentiator with a discontinuous right‐hand side. We consider the family of arbitrary‐order homogeneous differentiators, which includes these special cases.
Benjamin Calmbach, Jaime A. Moreno, Johann Reger +2 more
wiley +1 more source

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