Results 51 to 60 of about 22,306 (244)

Oncolytic Probiotics with Molecular Pili for Solid Tumor Therapy

Advanced Science, EarlyView.
This study identifies Lactobacillus rhamnosus as an intrinsic oncolytic agent that triggers tumor metabolic collapse via calcium‐dependent ROS bursts. By chemically anchoring collagen‐targeting “molecular pili” to the bacterial surface, the engineered non‐transgenic probiotic (LR@MP) achieves targeted colonization and potent solid tumor suppression ...
Haodong Ge, Chengsheng Ding, Xiao Yang, Si Gao, Changjie Yang, Yuchen Hou, Hongye Wang, Linke Bian, Hao Zhong, Yifan Qu, Luyang Zhang, Junjun Ma, Zhengwei Cai, Wenguo Cui, Minhua Zheng   +14 more
wiley   +1 more source

Cognition by description

Filosofia Unisinos, 2016
One important aspect of the faculty of language, as understood in generative grammar, is its capacity to form operator-variable structures. Such structures are crucial for definite descriptions, as understood in the broadly Russellian tradition.
John Bolender
doaj   +1 more source

Liver Stiffness Rises Early in MASLD and Drives Inflammation, Lipid Dysmetabolism, and Fibrosis via Piezo1–YAP Mechanotransduction

Advanced Science, EarlyView.
Progressive stiffening of the hepatic extracellular matrix and free fatty acid overload activate the mechanosensor Piezo1 in steatotic hepatocytes, inducing calcium influx and nuclear translocation of Yes‐associated protein. YAP‐dependent nuclear signaling further drives inflammatory and fibrotic gene programs, lipid metabolic reprogramming, and ...
Juan Ma, Ning Xie, Ziwei Wang, Xiru Liang, Yulong Han, Qiang Zhao, Ming Wang, Hongwei Lu, Wanyi Kou, William Alazawi, Jinhai Wang, Lu Li, Ning Liu, Na Liu, Haitao Shi, Feng Xu   +15 more
wiley   +1 more source

Non-Declarative Sentences and the Theory of Definite Descriptions

Principia: An International Journal of Epistemology, 2004
This paper shows that Russell’s theory of descriptions gives the wrong se-mantics for definite descriptions occurring in questions and imperatives. Depending on how that theory is applied, it either assigns nonsense to per-fectly meaningful questions and
John-Michael Kuczynski
doaj  

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Random Time‐Space Coding Metasurfaces for Spatial Control of the Temporal Statistics of Electromagnetic Fields

Advanced Science, EarlyView.
A probabilistic framework based on random time‐space coding metasurfaces enables control of the spatial distribution of electromagnetic fields temporal statistics. By tailoring the marginal and joint distributions of random codes, electromagnetic fields with desired mean and variance patterns are realized, enabling simultaneous transmission and jamming.
Jia Cheng Li, Jiang Han Bao, Che Liu, Tie Jun Cui   +3 more
wiley   +1 more source

Referentially Used Descriptions: A Reply to Devitt

European Journal of Analytic Philosophy, 2007
This paper continues an ongoing debate between Michael Devitt and me on referential uses of definite descriptions. He has argued that definite descriptions have referential meanings, and I have argued that they do not. Having previously rebutted the view
Kent Bach
doaj  

Exhaustivity in single bare wh-questions: A differential-analysis of exhaustivity

Glossa, 2018
Despite a large body of research, the linguistic nature of exhaustivity in single wh-questions is unresolved. Moreover, little empirical evidence exists as to which related structures pattern with bare wh-questions regarding exhaustivity.
Esther Ruigendijk, István Fekete, Petra Schulz   +2 more
doaj   +2 more sources

Rapid Room‐Temperature Synthesis of Te4+‐Doped Cs2ZrCl6 Vacancy‐Ordered Double Perovskites With Tunable Luminescence Triggered by Extreme Conditions for Advanced Optical Thermometry and Manometry

Advanced Science, EarlyView.
Through utilizing a proposed rapid room‐temperature precipitation method, the Te4+‐doped Cs2ZrCl6 vacancy‐ordered doubles with intense STE emission were synthesized. Via using the extreme conditions, i.e., temperature and pressure, stimulus, the luminescence properties of the resulting compounds are significantly modulated, endowing their promising ...
Zhiyu Pei, Yeshan Wu, Shuailing Ma, Tian Cui, Laihui Luo, Peng Du   +5 more
wiley   +1 more source

On What Is Not There. Quine, Meinong, and the Indispensability Argument

Humana.Mente: Journal of Philosophical Studies, 2013
Using the theory of definite descriptions, Russell  and, following him, Quine masterfully challenged Meinong’s Theory of Objects (TO). In this paper, firstly I try to show that although the Russell-Quine’s interpretation of TO has been taken seriously ...
Majid Davoody Beni
doaj