Results 21 to 30 of about 7,963,086 (297)

High-throughput screening identifies histone deacetylase inhibitors that modulate GTF2I expression in 7q11.23 microduplication autism spectrum disorder patient-derived cortical neurons

open access: yesMolecular Autism, 2020
Background Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental condition affecting almost 1% of children, and represents a major unmet medical need with no effective drug treatment available.
Francesca Cavallo   +18 more
doaj   +1 more source

Chromatin remodeler Activity-Dependent Neuroprotective Protein (ADNP) contributes to syndromic autism

open access: yesClinical Epigenetics, 2023
Background Individuals affected with autism often suffer additional co-morbidities such as intellectual disability. The genes contributing to autism cluster on a relatively limited number of cellular pathways, including chromatin remodeling.
Claudio Peter D’Incal   +10 more
doaj   +1 more source

Challenges in normative conceptualisation

open access: yesCommunicare, 2022
Technological developments continue to have an existential impact on the normative understanding of the community radio sector of South Africa. Advances, trends and changes in the technological sphere have meant that as researchers we need to keep up ...
Siyasanga M. Tyali
doaj   +1 more source

Determinisms [PDF]

open access: yesBelgrade Philosophical Annual, 2016
Determinism is usually understood as a commonly clear and obvious thesis. In the most of the actual literature a character of determinism is rarely enough explicitly underlined and we believe that it is the reason why common uses of the term often leads ...
Marko Vladimír
doaj   +1 more source

W stronę optymalizacji słownikowego objaśniania znaczeń

open access: yesStylistyka, 2020
In this paper, the author puts forward the following general hypotheses as a starting point for further enquiry: 1. Definitions and sets of definitions are developed on the basis of the results of exploration of linguistic reality and therefore they ...
Wojciech Chlebda
doaj   +1 more source

"Definition Modeling: To model definitions." Generating Definitions With Little to No Semantics

open access: yesCoRR, 2023
Definition Modeling, the task of generating definitions, was first proposed as a means to evaluate the semantic quality of word embeddings-a coherent lexical semantic representations of a word in context should contain all the information necessary to generate its definition.
Segonne, Vincent, Mickus, Timothee
openaire   +3 more sources

Main characteristics and construction conception of intelligent pipeline network

open access: yesYou-qi chuyun, 2020
At present, the problems of unclear definition and inconsistent understanding exist in the construction of intelligent pipeline network.Based on the definition of intelligent pipeline network proposed in the existing literatures, the following definition
Biyuan SHUI   +4 more
doaj   +1 more source

Paraphilias: definition, diagnosis and treatment [PDF]

open access: yes, 2013
There is a great deal of controversy concerning paraphilia, and defining what is normal versus deviant or disordered, given that this is to some degree dependent on cultural views of acceptability.
Alison, Laurence J   +3 more
core   +1 more source

THE TERRORISM IN POLITICAL RETROSPECT AND MODERN CONDITIONS

open access: yesСовременная наука и инновации, 2023
The article analyzes various aspects of terrorist activity in historical and political retrospect. The factors of mutual influence of the growth of international tension and the scale of terrorist activity are noted.The issues of the genesis and ...
S. V. Bachurin
doaj   +1 more source

Repeatability of Dixon magnetic resonance imaging and magnetic resonance spectroscopy for quantitative muscle fat assessments in the thigh

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2018
Background Changes in muscle fat composition as for example observed in sarcopenia or muscular dystrophy affect physical performance and muscular function, like strength and power. The purpose of the present study is to measure the repeatability of Dixon
Alexandra Grimm   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy