Results 71 to 80 of about 2,330,831 (316)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Updated interim U.S. SARS case definition [PDF]

open access: yes
Saturday, March 22, 2003, 18:18 EST (6 :18 PM EST)CDCHAN -00126-03-03-22-UPD-NFor purposes of case finding and surveillance in the United States, the March 17th CDC SARS case definition has been updated as follows:\u2022 Temperature must be measured ...

core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Dispatcher3 D1.1 - Technical resources and problem definition [PDF]

open access: yes, 2020
This deliverable starts with the proposal of Dispatcher3 and incorporates the development produced during the first five months of the project: activities on different workpackages, interaction with Topic Manager and Project Officer, and input received ...
De Falco, P.   +3 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Equivalent definitions of positive definiteness [PDF]

open access: yesPacific Journal of Mathematics, 1984
Maserick, P. H., Szafraniec, F. H.
openaire   +2 more sources

Market Definition: Use and Abuse [PDF]

open access: yes
A “market” can be rigorously and precisely defined quantitatively, but the information to do so is typically not available. Instead, markets are often defined based on qualitative information, leading to the possibility of errors.
Dennis W. Carlton
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Definition of Definition

open access: yesInternational Journal of Multidisciplinary Studies, 2022
K. Jayantha   +2 more
openaire   +1 more source

Computational thinking: the developing definition

open access: yes, 2013
Since Jeanette Wing’s use of the term computational thinking in 2006, various discussions have arisen seeking a robust definition of the phrase.
Woollard, John, Selby, Cynthia
core  

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