Results 231 to 240 of about 1,046,102 (312)

Compassion: Definitions and controversies [PDF]

, 2017
Gilbert, Paul
core  

Standardizing upper arm movement definitions across observational and sensor-based methods: A Delphi consensus study among European ergonomics experts. [PDF]

Scand J Work Environ Health
Frost AD, Forsman M, Brusaca LA, Holtermann A, Andersen LL, Søgaard K, Gupta N.   +6 more
europepmc   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Recommendations for studying the safety, efficacy and durability of intracranial aneurysm devices. [PDF]

Eur Stroke J
Volovici V, Meling TR, Krings T, Taussky P, Collins GS, Rinkel GJE, Vergouwen MDI.   +6 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Helping: definitions and purpose [PDF]

, 2013
Reid, H., Fielding, A.
core  

Humpty Dumpty Was Wrong - Consistency in Meaning Matters: Some Definitions of Privacy, Publicity, Secrecy, and Other Family Members

Secrecy and Society, 2016
Gary T. Marx
doaj  

Impact of Extreme Heat on Emergency Department Admissions for Childhood and Adult Asthma: An Evaluation of Earth Observations and Heat Wave Definitions. [PDF]

Geohealth
Corpuz B, Scott E, Zaitchik BF, Zeger S, Waugh D, Balasubramanian A, Madrigano J, Koehler K, Koehl R, McCormack M.   +9 more
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source