Results 51 to 60 of about 18,829 (261)

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Double Deflation and Aggregation

Environment and Planning A: Economy and Space, 1999
Published input—output tables in constant prices are relatively scarce. Therefore, input—output tables often have to be deflated by the practitioners themselves. The method of double deflation is used predominantly for this purpose. The present paper shows that the double-deflation method is subject to aggregation problems.
E Dietzenbacher, A R Hoen
openaire   +2 more sources

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

Advanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller, Nicole Vo, Utkarsh, Ivan Sokirniy, Justin Pritchard, Benjamin S. Freedman, Scott H. Medina   +6 more
wiley   +1 more source

Disconnected Stationary Solutions in 3D Kolmogorov Flow and Their Relation to Chaotic Dynamics

Mathematics
This paper aims to investigate the nonlinear transition to turbulence in generalized 3D Kolmogorov flow. The difference between this and classical Kolmogorov flow is that the forcing term in the x direction sin(y) is replaced with sin(y)cos(z).
Nikolay M. Evstigneev, Taisia V. Karamysheva, Nikolai A. Magnitskii, Oleg I. Ryabkov   +3 more
doaj   +1 more source

Deflating the Correspondence Intuition

Dialectica, 2005
A common objection against deflationist theories of truth is that they cannot do justice to the correspondence intuition, i.e. the intuition that there is an explanatory relationship between, for instance, the truth of 'Snow is white' and snow's being white. We scrutinize two attempts to meet this objection and argue that both fail.
Hindriks, F.A., Douven, I.
openaire   +3 more sources

Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution

Advanced Science, EarlyView.
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida, Yanghao Zhong, Akiko Kumagai, William G. Dunphy, Shasha Chong   +4 more
wiley   +1 more source

Statistical evaluation of the degree of nominal convergence of the inflation rate in Romania [PDF]

Revista Română de Statistică, 2011
Nominal convergence is a process that is characterised by the gradual harmonisation, to a relatively high degree, of the national institutions and policies of the Member States with those of the EU, in the monetary and financial fields.The birth of ...
Mihai GHEORGHE
doaj  

Lactation is Associated with Accelerated Postpartum Pelvic Floor Muscle Recovery in a Pregnant Simulated Birth Injury Model

Advanced Science, EarlyView.
ABSTRACT Healthy pelvic floor muscles (PFMs) are essential for proper pelvic floor function. The biggest risk factor for PFM dysfunction is injury sustained during vaginal childbirth, yet the factors that facilitate or impair PFM recovery from birth injury remain unknown.
Bianca L. Peña, Khushi M. Diwakar, Hillary K. Tran, Selena Cao, Celeste E. Lintz, Laila N. Hayes, Marianna Alperin, Karen L. Christman   +7 more
wiley   +1 more source

Interacting Parallel Fluidic Hysterons

Advanced Science, EarlyView.
The parallel coupling of fluidic hysterons is introduced, establishing advanced functionalities in inflatable soft systems. A pressure–volume framework reveals how preset volumes Δv∗${\Delta }v^*$ tune nonlinear interactions between hysterons and actuation sequences without changing architecture. Experiments validate the predictions, opening new routes
Katrien Stinissen, Franco Nicolas Piñan Basualdo, Benjamin Gorissen   +2 more
wiley   +1 more source

Inflation Dynamics in Post-Independence Rwanda [PDF]

Ovidius University Annals: Economic Sciences Series
This study examines the inflation dynamics in Rwanda from the 1970s to 2021, focusing on policies, trends, challenges, and opportunities in managing inflation. Secondary data sources were used for analysis.
Deogratius W.H. Kimolo, Nicholas M. Odhiambo, Sheilla Nyasha   +2 more
doaj