Results 21 to 30 of about 102,126 (216)

Effects of deformation rate and hydrated condition on the mechanical property of sandstone

矿业科学学报, 2020
According to a set of uniaxial compression experiments of sandstone, effects of deformation rate and hydrated condition on the compressive strength, elastic modulus, post-peak strain and acoustic emission(AE) characteristics were explored.A one ...
Teng Teng, Du Yubing, Chen Pengfei, Zhan Pengfei   +3 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Study on ultimate strength of box girder considering intact initialimperfections under cyclic bending moments

Zhongguo Jianchuan Yanjiu
ObjectivesTo fully consider intact initial imperfections, including welding initial deformation and residual stress, it is necessary to conduct a study on the plastic deformation distribution and ultimate strength of a box girder under different cyclic ...
Huwei CUI, Runwen HU, Qiyin DING
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

A microstructure sensitive model for deformation of Ti-6Al-4V describing Cast-and-Wrought and Additive Manufacturing morphologies

Materials & Design, 2018
Microstructural variations affect deformation response of materials and it is not presented in most of plastic flow prediction models. This work presents a unified description for the deformation response of Ti-6Al-4V (Ti-64) that successfully captures ...
M.A. Galindo-Fernández, K. Mumtaz, P.E.J. Rivera-Díaz-del-Castillo, E.I. Galindo-Nava, H. Ghadbeigi   +4 more
doaj   +1 more source

Short‐Term Response to Biologic Therapy in Psoriatic Arthritis Is Not Influenced by Disease Duration at Initiation of Therapy

Arthritis Care &Research, EarlyView.
Objective We aimed to determine whether the short‐term response to biologics in biologic‐naive psoriatic arthritis (PsA) is better in patients initiating biologic treatment early in the disease course. Methods Patients with PsA who started on biologic therapy from the year 2000 to 2025 were included for analysis.
Sung Min Cho, Shangyi Gao, Daniel Pereira, Richard J. Cook, Dafna D. Gladman   +4 more
wiley   +1 more source

Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout

Arthritis Care &Research, EarlyView.
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo, Bhavisha Desai, Abiola Oladapo, Nana Kragh, Rebekah Zincavage, Brad Padilla, Naomi Schlesinger   +6 more
wiley   +1 more source

Slip-dominated deformation mechanisms and tensile anisotropy of rolled Mg-6.3Gd-3Li-2Zn-0.5Al alloy based on crystal plasticity analysis

Journal of Magnesium and Alloys
In this work, mechanical properties, the tensile anisotropy, and deformation mechanisms during tensile testing of rolled Mg-6.3Gd-3Li-2Zn-0.5Al alloys (R2 and R4) were analyzed with Visco-Plastic Self-Consistent (VPSC) model and material characterization
Xiaohua Zhang, Jiaqi Li, Lin Wang, Yuansheng Cheng, Wei Lei, Qiang Chen   +5 more
doaj   +1 more source

Estimating the Prevalence and Incidence of Symptomatic Hand Osteoarthritis in the Netherlands Using Primary Care Electronic Health Records

Arthritis Care &Research, EarlyView.
Objective Estimating the incidence and prevalence of symptomatic hand osteoarthritis (OA) in the Dutch population using a validated algorithm that integrates free‐text data from primary care electronic health records (EHRs). Methods This retrospective cohort study used the Integrated Primary Care Information database, including EHRs from approximately ...
Onur Kaya, Jacoline van den Driest, Laura Struik, Margreet Kloppenburg, Ruud Selles, Daniel Prieto Alhambra, Sita Bierma‐Zeinstra, Dieuwke Schiphof   +7 more
wiley   +1 more source