Results 51 to 60 of about 461,188 (415)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Scoliosis Surgery in Cystic Fibrosis: Surgical Considerations and the Multidisciplinary Approach of a Rare Case

open access: yesCase Reports in Orthopedics, 2016
Spinal deformity in patients with cystic fibrosis (CF) is usually mild requiring no treatment. These patients are rarely considered as surgical candidates for scoliosis correction, as the pulmonary condition and other comorbidities increase the risk of ...
George I. Mataliotakis   +5 more
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Prediction of Fishman’s skeletal maturity indicators using artificial intelligence

open access: yesScientific Reports, 2023
The present study aimed to evaluate the performance of automated skeletal maturation assessment system for Fishman’s skeletal maturity indicators (SMI) for the use in dental fields.
Harim Kim   +6 more
doaj   +1 more source

Population-based normative data for the Scoliosis Research Society 22r, EQ-5D, and VAS questionnaires among individuals aged 20 to 69 years

open access: yesBone & Joint Open, 2022
Aims To provide normative data that can assess spinal-related disability and the prevalence of back or leg pain among adults with no spinal conditions in the UK using validated questionnaires.
Athanasios I. Tsirikos, Sarah J. Wordie
doaj   +1 more source

Conformity, deformity and reformity [PDF]

open access: yes, 2015
In any given field of artistic practice, practitioners position themselves—or find themselves positioned—according to interests and allegiances with specific movements, genres, and traditions. Selecting particular frameworks through which to approach the
Brown, Michael, Wilson, Chris
core   +2 more sources

Liaison and deformation

open access: yesJournal of Pure and Applied Algebra, 1986
The relation between liaison and some notions from deformation theory (as rigidity, the number of generators of the normal module, smoothability) is studied. Let \(P=k[[X]]\) be a power series ring over a field k of characteristic zero. Let I be a perfect P-ideal and let J be geometrically linked to I with respect to a regular sequence \(\alpha ...
openaire   +2 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Chitosan modified with PAP as a promising delivery system for melatonin in the treatment of osteoporosis: targeting the divalent metal transporter 1

open access: yesJournal of Biological Engineering
The demands for novel and efficient therapies have gradually increased with the rising concerns of osteoporosis (OP). The most popular method in promoting bone regeneration during osteoporotic conditions consists of loading bioactive materials with ...
Weilin Zhang   +10 more
doaj   +1 more source

Accuracy and efficiency of automatic tooth segmentation in digital dental models using deep learning

open access: yesScientific Reports, 2022
This study evaluates the accuracy and efficiency of automatic tooth segmentation in digital dental models using deep learning. We developed a dynamic graph convolutional neural network (DGCNN)-based algorithm for automatic tooth segmentation and ...
Joon Im   +7 more
doaj   +1 more source

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