Results 61 to 70 of about 380,720 (374)

THE PREVENTION OF DEFORMITY. [PDF]

JAMA: The Journal of the American Medical Association, 1902
While the entire medical profession of this generation are earnestly striving to better the condition of the human race by the prevention of disease, it seems an opportune time also to enlist their efforts toward the prevention of the many deformities of the body which surgeons are called upon to treat.
openaire   +3 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Proximal junctional failure prevention in adult spinal deformity surgery utilizing interlaminar fixation constructs

Orthopedic Reviews, 2019
Proximal junctional kyphosis (PJK) is a common complication following fusion for Adult Spinal Deformity. PJK and proximal junctional failure (PJF) may lead to pain, neurological injury, reoperation, and increased healthcare costs.
Alan H. Daniels, Shyam A. Patel, Daniel B.C. Reid, Burke Gao, Eren O. Kuris, Jacob M. Babu, J. Mason Depasse   +6 more
doaj   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Modified Trochanteric Flip Osteotomy in Varus Intertrochanteric Osteotomy for Treatment of Legg–Calvé–Perthes Disease

Children
Background/Objectives: Legg–Calvé–Perthes disease (LCPD) presents challenges in treatment due to its varied course and unclear etiology. This study aimed to evaluate the efficacy of combining proximal femoral varus osteotomy (PFVO) with a modified ...
Andrea Laufer, Carina Antfang, Georg Gosheger, Adrien Frommer, Gregor Toporowski, Henning Tretow, Robert Roedl, Bjoern Vogt   +7 more
doaj   +1 more source

Dandy-Walker Syndrome Associated with Scoliosis: Clinical Presentation, Preoperative Assessment, and Treatment

Case Reports in Orthopedics, 2020
Dandy-Walker syndrome (DWS) affects the posterior cranial fossa resulting in characteristic dysmorphic facial and body features. Scoliosis is not typically reported as an extracranial manifestation of this condition.
Athanasios I. Tsirikos, Sarah J. Wordie
doaj   +1 more source

Focal osteolysis and corrosion at the junction of Precice Stryde intramedullary lengthening device: preliminary clinical, radiological, and metallurgic analysis of 57 lengthened segments

Bone & Joint Research, 2021
Aims: This study aims to enhance understanding of clinical and radiological consequences and involved mechanisms that led to corrosion of the Precice Stryde (Stryde) intramedullary lengthening nail in the post market surveillance era of the device ...
Adrien Frommer, Robert Roedl, Georg Gosheger, Julian Hasselmann, Cordula Fuest, Gregor Toporowski, Andrea Laufer, Henning Tretow, Martin Schulze, Bjoern Vogt   +9 more
doaj   +1 more source

Reliability assessment of a novel cervical spine deformity classification system.

Journal of Neurosurgery : Spine, 2015
OBJECT Despite the complexity of cervical spine deformity (CSD) and its significant impact on patient quality of life, there exists no comprehensive classification system.
C. Ames, Justin S. Smith, R. Eastlack, D. Blaskiewicz, C. Shaffrey, F. Schwab, S. Bess, Han-Jo Kim, G. Mundis, E. Klineberg, M. Gupta, M. O’Brien, R. Hostin, J. Scheer, T. Protopsaltis, Kai-Ming G. Fu, R. Hart, T. Albert, K. Riew, M. Fehlings, V. Deviren, V. Lafage, _   +22 more
semanticscholar   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Comparison of histomorphometric and radiographic effects of growth guidance with tension-band devices (eight-Plate and FlexTack) in a pig model

Acta Orthopaedica, 2021
Background and purpose — Temporary hemiepiphysiodesis for growth modulation in skeletally immature patients is a long-known technique. Recently the use of tension-band devices has become popular.
Julia Sattelberger, Hauke Hillebrand, Georg Gosheger, Andrea Laufer, Adrien Frommer, Sebastian Appelbaum, Ahmed Abdul-Hussein Abood, Martin Gottliebsen, Ole Rahbek, Bjarne Moller-Madsen, Robert Roedl, Bjoern Vogt   +11 more
doaj   +1 more source