Results 81 to 90 of about 472,775 (419)

'Windswept deformity'. [PDF]

open access: yesArchives of Disease in Childhood, 1983
We describe 8 children with 'windswept deformity'--a valgus deformity of 1 knee in association with a varus deformity of the other. The disease is a physeal osteochondrosis and conservative treatment with serial corrective plaster casts is as effective as corrective osteotomies.
O O, Oni, H, Keswani, M O, Aganga
openaire   +2 more sources

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

A Variational Beam Model for Failure of Cellular and Truss‐Based Architected Materials

open access: yesAdvanced Engineering Materials, EarlyView., 2023
Herein, a versatile and efficient beam modeling framework is developed to predict the nonlinear response and failure of cellular, truss‐based, and woven architected materials. It enables the exploration of their design space and the optimization of their mechanical behavior in the nonlinear regime. A variational formulation of a beam model is presented
Konstantinos Karapiperis   +3 more
wiley   +1 more source

The impact of rheumatoid arthritis on foot function in the early stages of disease: a clinical case series [PDF]

open access: yes, 2006
BACKGROUND Foot involvement occurs early in rheumatoid arthritis but the extent to which this impacts on the structure and function leading to impairment and foot related disability is unknown. The purpose of this study was to compare clinical disease
Emery, P.   +3 more
core   +3 more sources

Treatment of hallux valgus deformity

open access: yesEFORT Open Reviews, 2016
Hallux valgus deformity is a very common pathological condition which commonly produces painful disability. It is characterised as a combined deformity with a malpositioning of the first metatarsophalangeal joint caused by a lateral deviation of the ...
Lukas Fraissler   +4 more
semanticscholar   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Topology Optimization of Lattice Support Structure for Cantilever Beams Fabricated Via Laser Powder Bed Fusion

open access: yesAdvanced Engineering Materials, EarlyView., 2023
A numerical scheme is presented to design a lattice support for metallic components additively built via laser powder bed fusion. Results show that thermal‐induced distortion can be respectively reduced by 69%, 58%, and 50% in comparison to a uniform lattice, a fully solid support, and a truss‐based lattice support.
Jiazheng Hu   +2 more
wiley   +1 more source

Proximal junctional failure prevention in adult spinal deformity surgery utilizing interlaminar fixation constructs

open access: yesOrthopedic Reviews, 2019
Proximal junctional kyphosis (PJK) is a common complication following fusion for Adult Spinal Deformity. PJK and proximal junctional failure (PJF) may lead to pain, neurological injury, reoperation, and increased healthcare costs.
Alan H. Daniels   +6 more
doaj   +1 more source

Focal osteolysis and corrosion at the junction of Precice Stryde intramedullary lengthening device: preliminary clinical, radiological, and metallurgic analysis of 57 lengthened segments

open access: yesBone & Joint Research, 2021
Aims: This study aims to enhance understanding of clinical and radiological consequences and involved mechanisms that led to corrosion of the Precice Stryde (Stryde) intramedullary lengthening nail in the post market surveillance era of the device ...
Adrien Frommer   +9 more
doaj   +1 more source

Kinematic Foot Types in Youth with Equinovarus Secondary to Hemiplegia [PDF]

open access: yes, 2015
Background Elevated kinematic variability of the foot and ankle segments exists during gait among individuals with equinovarus secondary to hemiplegic cerebral palsy (CP). Clinicians have previously addressed such variability by developing classification
Corcos, Daniel M.   +6 more
core   +2 more sources

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