Results 1 to 10 of about 7,813 (185)

Degeneracy: Demystifying and destigmatizing a core concept in systems biology

Complexity, 2014
Often relegated to the methods section of genetic research articles, the term “degeneracy” is regularly misunderstood and its theoretical significance widely understated. Degeneracy describes the ability of different structures to be conditionally interchangeable in their contribution to system functions.
Paul H. Mason
openaire   +2 more sources

Organizational Principles of Biological Systems [PDF]

Biology
How does the complex, adaptive, and autonomous organization of life emerge from the laws of physics and information? This review argues that the answer lies in a convergent set of universal organizational principles that constitute a physical and ...
Roberto Carlos Navarro-Quiroz, Kelvin Navarro Quiroz, Victor Navarro Quiroz, Antonio Gabucio, Ricardo Fernández-Cisnal, Noelia Geribaldi-Doldán, Cecilia Fernandez-Ponce, Ismael Sánchez Gomar, Yesit Bello Lemus, Eloina Zárate Peñata, Lisandro A. Pacheco-Lugo, Leonardo C. Londoño-Pacheco, Martha Rebolledo Cobos, Antonio Acosta Hoyos, Diana Pava Garzon, José Luis Villarreal Camacho, Elkin Navarro Quiroz   +16 more
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Sex and Gender Identities Are Emergent Properties of Neural Complexity [PDF]

Behavioral Sciences
We investigate why the remarkable diversity of human identity, including gender fluidity, non-binary roles, and varied sexual orientations, is fundamentally rooted in the evolutionary and neurocognitive complexity of the human brain.
Simone Di Plinio, Olatz Etxebarria-Perez-De-Nanclares   +1 more
doaj   +2 more sources

Quantum Biology Research Meets Pathophysiology and Therapeutic Mechanisms: A Biomedical Perspective

Quantum Reports, 2022
The recent advances of quantum biology suggest a potential role in biomedical research. Studies related to electromagnetic fields, proton pumping in mitochondrial respiratory chain, quantum theory of T-cell receptor (TCR)-degeneracy, theories on ...
Laura Calvillo, Veronica Redaelli, Nicola Ludwig, Abdallah Barjas Qaswal, Alice Ghidoni, Andrea Faini, Debora Rosa, Carolina Lombardi, Martino Pengo, Patrizia Bossolasco, Vincenzo Silani, Gianfranco Parati   +11 more
doaj   +1 more source

Spontaneous symmetry breaking as a law of nature

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2023
In a semi-review paper, it was discussed the notion of symmetry of polyatomic systems defined as invariance under transformations, and show that this important property of atomic matter is extremely vulnerable, and may undergo internal breakdown, subject
Bersuker Isaac
doaj   +1 more source

Design of typical genes for heterologous gene expression

Scientific Reports, 2022
Heterologous protein expression is an important method for analysing cellular functions of proteins, in genetic circuit engineering and in overexpressing proteins for biopharmaceutical applications and structural biology research.
Dominic Simm, Blagovesta Popova, Gerhard H. Braus, Stephan Waack, Martin Kollmar   +4 more
doaj   +1 more source

GaAs-chip-based mid-infrared supercontinuum generation

Light: Science & Applications, 2023
The mid-infrared spectral region opens up new possibilities for applications such as molecular spectroscopy with high spatial and frequency resolution. For example, the mid-infrared light provided by synchrotron sources has helped for early diagnosis of ...
Geoffroy Granger, Myriam Bailly, Hugo Delahaye, Cristian Jimenez, Idris Tiliouine, Yann Leventoux, Jean-Christophe Orlianges, Vincent Couderc, Bruno Gérard, Rezki Becheker, Said Idlahcen, Thomas Godin, Ammar Hideur, Arnaud Grisard, Eric Lallier, Sébastien Février   +15 more
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Asymptotic estimates of the solution of the boundary value problem for singularly perturbed integro-differential equations

Вестник КазНУ. Серия математика, механика, информатика, 2020
The mathematical models of many processes in physics, astrophysics, chemistry, biology, mechanics and technology are differential and integro-differential equations containing small parameters at the highest derivatives.
M. Dauylbayev, N. Aviltay, B. Kadirbekov
doaj   +1 more source

Toward First Principle Medical Diagnostics: On the Importance of Disease-Disease and Sign-Sign Interactions

Frontiers in Physics, 2017
A fundamental problem in medicine and biology is to assign states, e.g., healthy or diseased, to cells, organs or individuals. State assignment or making a diagnosis is often a nontrivial and challenging process and, with the advent of omics technologies,
Abolfazl Ramezanpour, Abolfazl Ramezanpour, Alireza Mashaghi   +2 more
doaj   +1 more source

Epigenetic pacemaker: closed form algebraic solutions

BMC Genomics, 2020
Background DNA methylation is widely used as a biomarker in crucial medical applications as well as for human age prediction of very high accuracy. This biomarker is based on the methylation status of several hundred CpG sites.
Sagi Snir
doaj   +1 more source