Results 91 to 100 of about 1,564,798 (354)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

On a hyperbolic Keller-Segel system with degenerate nonlinear fractional diffusion

Networks and Heterogeneous Media, 2016
We investigate a Keller-Segel model with quorum sensing anda fractional diffusion operator. This model describes thecollective cell movement due to chemical sensing with fluxlimitation for high cell densities and with anomalous mediarepresented by a ...
Kenneth H. Karlsen, Süleyman Ulusoy
doaj   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

Thermal Energy Diffusion Incorporating Generalized Einstein Relation for Degenerate Semiconductors

Applied Sciences, 2017
The currently used generalized Einstein relation for degenerate semiconductors with isotropic nonparabolic energy bands produces physically improper results, as well as losing numerical accuracy for large values of nonparabolicity parameters at room ...
Jang Jyegal
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Enhanced phase and charge diffusion due to radio-frequency/microwave excitation in Bloch transistors

AIP Advances, 2013
Current-voltage characteristics and switching current of Bloch transistors under radio-frequency/microwave excitations were experimental studied, respectively revealing pronounced summational superconducting phase diffusion and central-island charge ...
Saxon Liou, Watson Kuo
doaj   +1 more source

Local and Global Well-Posedness for Aggregation Equations and Patlak-Keller-Segel Models with Degenerate Diffusion

, 2010
Recently, there has been a wide interest in the study of aggregation equations and Patlak-Keller-Segel (PKS) models for chemotaxis with degenerate diffusion.
Adams R A, Ambrosio L A, Andrea L Bertozzi, Bertozzi A L, Biler P, Blanchet A, Blanchet A Carlen E Carrillo J A, Calvez V, Carrillo J A, Carrillo J A Rosado J, Di Francesco M, Dolbeault J, Horstmann D, Jacob Bedrossian, Karch G Suzuki K, Killip R Vişan M, Lieberman G M, Lions P L, Majda A, Milewski P A, Nancy Rodríguez, Richard I Lapidus Levandowsky M, Stein E, Sugiyama Y, Sugiyama Y, Sugiyama Y, Vázquez J L, Yudovich V I   +27 more
core   +3 more sources

Gradient estimates for degenerate diffusion equations. I

Mathematische Annalen, 1982
SynopsisWe establish upper and lower bounds for various norms of solutions and their gradients for the equation ut = div (|∇u|m−1 ∇u) in ℝN in terms of the norms of the initial data. Based on the L∞ estimate of ∇u, we conclude that u(x, t) is Lipschitz continuous in space-time, for all t>0, whenever u(x,0) is in L1(ℝN).
Alikakos, Nicholas D., Rostamian, Ruben
openaire   +2 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

The uniqueness of a nonlinear diffusion equation related to the p-Laplacian

Journal of Inequalities and Applications, 2018
Consider a nonlinear diffusion equation related to the p-Laplacian. Different from the usual evolutionary p-Laplacian equation, the equation is degenerate on the boundary due to the fact that the diffusion coefficient is dependent on the distance ...
Huashui Zhan
doaj   +1 more source