Results 151 to 160 of about 1,564,798 (354)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Quenching for singular and degenerate quasilinear diffusion equations

open access: yesElectronic Journal of Differential Equations, 2013
This article concerns the quenching phenomenon of the solution to the Dirichlet problem of a singular and degenerate quasilinear diffusion equation. It is shown that there exists a critical length for the special domain in the sense that the solution ...
Yuanyuan Nie, Chunpeng Wang, Qian Zhou
doaj  

A New Kind of Weak Solution of Non-Newtonian Fluid Equation

open access: yesJournal of Function Spaces, 2017
If the non-Newtonian fluid equation with a diffusion coefficient is degenerate on the boundary, the weak solution lacks the regularity to define the trace on the boundary.
Huashui Zhan, Bifen Xu
doaj   +1 more source

What Is the Role of Giant Endosomal Sorting Complexes Required for Transport (ESCRT) Structures in T Cell Activation?

open access: yesAdvanced Biology, EarlyView.
The article explores the discovery of unusually large, ring‐shaped ESCRT protein structures formed by immune and stromal cells. It investigates their formation, composition, and potential roles in immune synapse formation. The findings challenge assumptions about their function in immunological synapses, suggesting an exclusive role in maintaining ...
Anthi Psoma   +3 more
wiley   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez   +5 more
wiley   +1 more source

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