Results 151 to 160 of about 1,519 (300)

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

Smoothness and stability in the Alt-Phillips problem. [PDF]

Math Ann
Carducci M, Tortone G.
europepmc   +1 more source

Strongly interacting bumps for the schrodinger-newton equations

, 2009
We study concentrated bound states of the Schrodinger-Newton equations Moroz, Penrose and Tod proved the existence and uniqueness of ground states.
Winter, M, Wei, J
core  

Structurally Complex Precipitates Enhance Strength‐Ductility Synergy in a Duplex Medium Entropy Alloy

Advanced Science, EarlyView.
Strong‐yet‐ductile precipitation‐hardening alloys require novel microstructural complexity of precipitates in particularly at cryogenic condition, to constantly impart strain hardening of hard‐and‐brittle precipitates. The present work creates innovative structurally complex precipitates assembled with dispersed nanocores and a chemical‐heterogeneity ...
Shaohua Gao, Yang Yang, Xiaoxuan Fan, Jinyu Zhang, Shuaiyang Liu, Jiao Li, Hui Wang, Wenli Song, Gang Liu, Jun Sun   +9 more
wiley   +1 more source

Gradient regularity for widely degenerate elliptic partial differential equations. [PDF]

SN Partial Differ Equ Appl
Strunk M.
europepmc   +1 more source

Entropy Decoding the Fundamental Law of Phase Competition in Glass Formation

Advanced Science, EarlyView.
We validate the integration of intermetallic and eutectic phases as initial phases for composition design. The phase competition mechanism in glass formation is quantitatively clarified based on the melting entropy of competing phases. Glass‐forming ability is modulated by tuning phase competition via the melting entropy of initial phases.
Benke Huo, Zhengqing Cai, Bingtao Wang, Zhenqiang Song, Shi‐Dong Feng, Zijing Li, Xingjun Liu, Li‐Min Wang   +7 more
wiley   +1 more source

Optical wave propagation in magneto-optic waveguides with generalized anti-cubic model. [PDF]

Sci Prog
Baber MZ, Yasin MW, Ahmed N, Arif K, Ceesay B.   +4 more
europepmc   +1 more source

Machine‐Learning‐Enhanced Printed Vertical Magnetoresistive Sensors for Transparent, Flexible, Multimodal Interactive Magnetoelectronics

Advanced Science, EarlyView.
This study presents printed magnetoresistive sensors with a vertically aligned architecture that enables high optical transparency and mechanical flexibility. By integrating deep learning for the analysis of complex spatiotemporal signal patterns, the system further achieves intelligent multimodal interaction capabilities.
Rui Xu, Guannan Mu, Oleksandr V. Pylypovskyi, Qihao Zhang, Rico Illing, René Hübner, Ran He, Andreas Knüpfer, Sebastian Lehmann, Olha Bezsmertna, Kornelius Nielsch, Denys Makarov   +11 more
wiley   +1 more source

Dynamical analysis and soliton solutions to (3+1)-dimensional extended quantum nonlinear Zakharov-Kuznetsov equation. [PDF]

Sci Rep
Fatima M, Abbas M, Higazy M, Anwar MN, Yousaf MZ, Birhanu A, Hamed YS.   +6 more
europepmc   +1 more source

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source