Results 41 to 50 of about 18,304 (280)

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Higher-order corrections of the hydrogen-like atoms: the effect of Darwin term

Arab Journal of Basic and Applied Sciences
The article extensively explores higher-order corrections of the time-independent non-degenerate perturbation theory, providing a thorough analysis of its fundamental principles.
Mahmood Jwailes, Imad Barghouthi, Qusay Atawnah   +2 more
doaj   +1 more source

Quantum coherence-control of thermal energy transport: the V model as a case study

New Journal of Physics, 2022
Whether genuine quantum effects, particularly quantum coherences, can offer an advantage to quantum devices is a topic of much interest. Here, we study a minimal model, the three-level V system coupled to two heat baths, and investigate the role of ...
Felix Ivander, Nicholas Anto-Sztrikacs, Dvira Segal   +2 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Ultrafast carrier dynamics in Landau-quantized graphene

Nanophotonics, 2015
In an external magnetic field, the energy of massless charge carriers in graphene is quantized into non-equidistant degenerate Landau levels including a zero-energy level.
Wendler Florian, Knorr Andreas, Malic Ermin   +2 more
doaj   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Mitochondrial DNA Variants Mediate Energy Production and Expression Levels for CFH, C3 and EFEMP1 Genes: Implications for Age-Related Macular Degeneration [PDF]

PLoS ONE, 2013
Mitochondrial dysfunction is associated with the development and progression of age-related macular degeneration (AMD). Recent studies using populations from the United States and Australia have demonstrated that AMD is associated with mitochondrial (mt) DNA haplogroups (as defined by combinations of mtDNA polymorphisms) that represent Northern ...
Kenney, M. Cristina, Chwa, Marilyn, Atilano, Shari R, Pavlis, Janelle M, Falatoonzadeh, Payam, Ramirez, Claudio, Malik, Deepika, Hsu, Tiffany, Woo, Grace, Soe, Kyaw, Nesburn, Anthony B, Boyer, David S, Kuppermann, Baruch D, Jazwinski, S. Michal, Miceli, Michael V, Wallace, Douglas C, Udar, Nitin, Lukiw, Walter   +17 more
openaire   +6 more sources

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Deformed Oscillators with Two Double (Pairwise) Degeneracies of Energy Levels

Symmetry, Integrability and Geometry: Methods and Applications, 2007
A scheme is proposed which allows to obtain special $q$-oscillator models whose characteristic feature consists in possessing two differing pairs of degenerate energy levels.
Alexandre M. Gavrilik, Anastasiya P. Rebesh   +1 more
doaj  

Understanding multiple timescales in quantum dissipative dynamics: Insights from quantum trajectories

Physical Review Research
Open quantum systems with nearly degenerate energy levels have been shown to exhibit long-lived metastable states in the approach to equilibrium, even when modelled with certain Lindblad-form quantum master equations.
Matthew Gerry, Michael J. Kewming, Dvira Segal   +2 more
doaj   +1 more source