Results 51 to 60 of about 6,399 (264)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Studying behavior of the asymptotic solutions to P-Laplacian type diffusion-convection model [PDF]
مجلة جامعة الانبار للعلوم الصرفةThe rescaling method is presented to allow us to establish nonnegative local solutions to the evolution of the Cauchy problem (CP) of the nonlinear degenerate parabolic p-Laplacian process with conservation laws that are posed in one-dimensional space ...
Habeeb Aal-Rkhais, Ruba Qasim
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Some applications of the generalized Laplace transform and the representation of a solution to Sobolev-type evolution equations with the generalized Caputo derivative [PDF]
Bulletin of the Polish Academy of Sciences: Technical SciencesWe introduce the Sobolev-type multi-term μ-fractional evolution with generalized fractional orders with respect to another function. We make some applications of the generalized Laplace transform.
Mustafa Aydin, Nazim Mahmudov
doaj +1 more source
Network of interacting neurons with random synaptic weights [PDF]
ESAIM: Proceedings and Surveys, 2019 Since the pioneering works of Lapicque [17] and of Hodgkin and Huxley [16], several types of models have been addressed to describe the evolution in time of the potential of the membrane of a neuron.
Grazieschi Paolo +5 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Entropy solutions for nonlinear degenerate elliptic-parabolic-hyperbolic problems
Electronic Journal of Differential Equations, 2014 We consider the nonlinear degenerate elliptic-parabolic-hyperbolic equation $$ \partial_t g (u) - \Delta b (u) - \hbox{div} \Phi(u) = f (g (u) ) \quad \text{in } (0,T) \times \Omega, $$ where g and b are nondecreasing continuous functions, $\Phi$
Ning Su, Li Zhang
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Entropy, 2020 The approach based on the Wigner function is considered as a viable model of quantum transport which allows, in analogy with the semiclassical Boltzmann equation, to restore a description in the phase-space.
Vito Dario Camiola +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source