Results 11 to 20 of about 75,109 (198)

Irreversible Investment under L\'evy Uncertainty: an Equation for the Optimal Boundary [PDF]

open access: yes, 2014
We derive a new equation for the optimal investment boundary of a general irreversible investment problem under exponential L\'evy uncertainty. The problem is set as an infinite time-horizon, two-dimensional degenerate singular stochastic control problem.
Ferrari, Giorgio, Salminen, Paavo
core  

Finite-size corrections to quantized particle transport in topological charge pumps

open access: yes, 2017
We investigate the quantization of adiabatic charge transport in the insulating ground state of finite systems. Topological charge pumps are used in experiments as an indicator of topological order. In the thermodynamic limit the transport can be related
Fleischhauer, Michael, Li, Rui
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Heat Kernel Asymptotics, Path Integrals and Infinite-Dimensional Determinants

open access: yes, 2018
We investigate the short-time expansion of the heat kernel of a Laplace type operator on a compact Riemannian manifold and show that the lowest order term of this expansion is given by the Fredholm determinant of the Hessian of the energy functional on a
Ludewig, Matthias
core   +1 more source

Oscillations of neutrinos and mesons in quantum field theory [PDF]

open access: yes, 2001
This report deals with the quantum field theory of particle oscillations in vacuum. We first review the various controversies regarding quantum-mechanical derivations of the oscillation formula, as well as the different field-theoretical approaches ...
Abazov   +227 more
core   +4 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Stochastic complexity of spin models: Are pairwise models really simple? [PDF]

open access: yes, 2018
Models can be simple for different reasons: because they yield a simple and computationally efficient interpretation of a generic dataset (e.g. in terms of pairwise dependences) - as in statistical learning - or because they capture the essential ...
Battistin, Claudia   +4 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Exponential mixing of the 3D stochastic Navier-Stokes equations driven by mildly degenerate noises [PDF]

open access: yes, 2009
We prove the strong Feller property and exponential mixing for 3D stochastic Navier-Stokes equation driven by mildly degenerate noises (i.e. all but finitely many Fourier modes are forced) via Kolmogorov equation approach.Comment: 31 pp.
Albeverio, Sergio   +2 more
core   +5 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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