Results 221 to 230 of about 157,424 (307)

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Indirubin and Retinoic Acid Show Binding Affinity to Monocyte Biomarker CSF3R in Parkinson's Disease

Journal of Clinical Laboratory Analysis, EarlyView.
Through single‐cell RNA‐sequencing and high‐dimensional weighted gene co‐expression network analysis, two monocyte‐related biomarkers (CSF3R, IFITM3) were identified in the peripheral blood of Parkinson's disease. Molecular docking revealed two targeted drugs (Indirubin and Retinoic acid).
Zhiwei Bao, Shao Zhi, Mao Jie
wiley   +1 more source

Effect of an increased dosage of statins on spinal degenerative joint disease: a retrospective cohort study. [PDF]

BMJ Open, 2018
Cheng YY, Kao CL, Lin SY, Chang ST, Wei TS, Chang SN, Lin CH.   +6 more
europepmc   +1 more source

The Impact of Vision Problems on Households' Incomes: Evidence From the 2019 and 2022 Rounds of the Turkey Health Survey

Journal of International Development, EarlyView.
ABSTRACT Vision problems reduce individuals' quality of life, and they also reduce their productivity as workers and consequently decrease their incomes. Most vision problems can be corrected with properly fitted eyeglasses, but many people with vision problems do not have such eyeglasses.
Paul Glewwe, Hasan Gul, Aysit Tansel, Suzanne Wisniewski   +3 more
wiley   +1 more source

Evaluation of serum cytokines in cats with and without degenerative joint disease and associated pain. [PDF]

Vet Immunol Immunopathol, 2017
Gruen ME, Gruen ME, Messenger KM, Thomson AE, Griffith EH, Aldrich LA, Vaden S, Lascelles BDX.   +7 more
europepmc   +1 more source

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad, Abdulrahman A Alsayegh, Anjum Khanam, Awais Ahmed, António Raposo, Farkad Bantun, Md Zeyaullah, Ahmad O Babalghith, Abdullah F Aldairi, Boshra Mozaffar, Mohammed F Bajahzer, Mohamed H Abdelrahman, Mohammad Intakhab Alam   +12 more
wiley   +1 more source

Megavoltage Radiotherapy for the Treatment of Degenerative Joint Disease in Dogs: Results of a Preliminary Experience in an Italian Radiotherapy Centre. [PDF]

Front Vet Sci, 2018
Rossi F, Cancedda S, Leone VF, Rohrer Bley C, Laganga P.   +4 more
europepmc   +1 more source

Liver Stiffness Characterization of OGTLKO Mouse Model of Progressive Liver Fibrosis

Journal of Ultrasound in Medicine, EarlyView.
Objectives O‐GlcNAcylation plays a key regulatory role in hepatic physiology, and its disruption leads to fibrosis in liver‐specific OGT knockout mice (OGTLKO), making this model valuable for studying advanced metabolic dysfunction‐associated steatohepatitis (MASH).
Gilles Renault, Lenin Chinchilla, Lourdes Massengo, Pierre Monbernard, Fadila Benhamed, Marion Regnier, Raphael Denis, Catherine Postic, Anthony Novell, Jean‐Luc Gennisson   +9 more
wiley   +1 more source

Levels of Matrix-Degrading Enzymes and Lubricin in Patients With Degenerative Joint Disease Requiring Arthroplasty. [PDF]

Clin Appl Thromb Hemost, 2018
Wanderling C, Liles J, Davis E, Schmitt D, Statz S, Guler N, Hoppensteadt D, Fareed J, Hopkinson W.   +8 more
europepmc   +1 more source

Value of 2‐Dimensional Shear‐Wave Elastography in Assessing Tibial Nerve Stiffness in Diabetic Peripheral Neuropathy

Journal of Ultrasound in Medicine, EarlyView.
Objectives The morphological alterations of the tibial nerve in patients with diabetes mellitus, both with and without diabetic peripheral neuropathy (DPN), are challenging to differentiate using B‐mode ultrasound. In this study, we assessed the stiffness changes of the tibial nerve by 2‐dimensional shear‐wave elastography (2D‐SWE). Methods We gathered
Jiafan Li, Shaozhi Cai, Yuxia Zhai, Ruoting Zheng, Junbin Du   +4 more
wiley   +1 more source