Results 231 to 240 of about 157,424 (307)

Melatonin Exerts Chondroprotective Effects Against Osteoarthritis by Promoting PI3K/AKT/FoxO3‐Mediated Mitophagy

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang, Gang Zhang, Ying‐Kai Ma, Xin‐Nan Ma, Song‐Cen Lv   +4 more
wiley   +1 more source

Caregiver placebo effect in analgesic clinical trials for cats with naturally occurring degenerative joint disease-associated pain. [PDF]

Vet Rec, 2017
Gruen ME, Dorman DC, Lascelles BDX.
europepmc   +1 more source

USP7 Regulates TRPV1 Deubiquitination to Mediate Chondrocyte Ferroptosis and Alleviate Osteoarthritis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease characterized by chondrocyte dysfunction. In this study, we explored the function and mechanism of ubiquitin‐specific protease 7 (USP7) in chondrocyte ferroptosis in OA. The USP7, TRPV1, collagen II, and GPX4 levels in knee joint tissue were detected using immunohistochemistry ...
Jun Li, Ding Chen, Wei‐Ye Zhong
wiley   +1 more source

Adolescence risk factors for meniscus and ligamentous knee injuries in adulthood: A longitudinal study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Our aim is to investigate the influence of adolescent health‐related behaviours on the occurrence of meniscus and ligament injuries in a large cohort of Finnish adolescents with an average 27‐year follow‐up. Methods The baseline data were surveys conducted biannually from 1981 to 1997, and these were individually linked to outcomes, as
Matias Vaajala, Alisa Teuho, Rasmus Liukkonen, Ville Ponkilainen, Arja Rimpelä, Leena K. Koivusilta, Ville M. Mattila   +6 more
wiley   +1 more source

Age at the time of surgery does not compromise the outcome of deepening trochleoplasty: Results from under and over 30 years old

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to evaluate whether age at the time of surgery influences patient‐reported outcome measures (PROMs) in patients undergoing tailored surgical treatment for lateral patellar dislocation (LPD), including deepening trochleoplasty (TP). Methods This retrospective cohort study used a prospectively maintained database.
Danko Dan Milinkovic, Felix Zimmermann, Julian Fluegel, Sebastian Schmidt, Peter Balcarek   +4 more
wiley   +1 more source

Isolated meniscal repair, medial meniscus repair and older age increase failure risk after all‐inside meniscal repair: A cohort study of 2264 patients

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the overall failure rate and assess factors influencing the failure of modern all‐inside meniscal repair. Methods Patients who underwent all‐inside meniscal repair at Capio Artro Clinic, Stockholm, Sweden, from January 2015 to June 2022, were identified.
Christoffer von Essen, Riccardo Cristiani, Carolina Kekki, Dzan Rizvanovic, Anders Stålman   +4 more
wiley   +1 more source

Contribution of neuromuscular Impairment to physical functional Status in Patients with Lumbar Spinal Stenosis [PDF]

, 1994
Fossel, Anne H., Katz, Jeffrey N., Liang, Matthew H., Lipson, Stephen J., Stucki, Gerold   +4 more
core  

Increased reoperation rates after meniscus repair compared to arthroscopic partial meniscectomy: Data from a comprehensive clinical cohort with up to 10 years follow‐up

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To investigate the rates of knee reoperation and medical complications after meniscal repair versus partial meniscectomy (APM) up to 10 years after surgery. Methods All patients ≥ 15 years old operated for a meniscal tear with meniscus repair or partial meniscectomy at Scania University Hospital were included, between year 2010 and ...
Fredrik Boric‐Persson, Aleksandra Turkiewicz, Martin Englund, Paul Neuman   +3 more
wiley   +1 more source

Longitudinal correlation between X‐ray and MRI findings in medial compartment knee osteoarthritis: Insights into early cartilage loss and structural changes

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
ABSTRACT Purpose Knee osteoarthritis (OA) is a common joint disorder assessed using radiographic (X‐ray) and magnetic resonance imaging (MRI). While X‐rays are accessible, MRI provides detailed insights into meniscus and cartilage. Few studies have evaluated the correlation between X‐ray and MRI findings in knee OA longitudinally.
Do Weon Lee, Ji‐Sahn Kim, Hyuk‐Soo Han, Du Hyun Ro   +3 more
wiley   +1 more source

Step‐by‐step insight into gait analysis: A narrative review unlocking knee biomechanics

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Gait analysis offers a powerful tool for clinical and orthopaedic decision‐making. By quantifying spatiotemporal, kinematic and kinetic parameters during walking, it provides a dynamic window into joint function that static imaging cannot capture.
Giovanni Spallone, Letizia Mancini, Arianna Carnevale, Stefano Campi, Alessandro de Sire, Emiliano Schena, Pieter D'Hooghe, Michael T. Hirschmann, Rocco Papalia, Umile Giuseppe Longo   +9 more
wiley   +1 more source