Results 71 to 80 of about 5,097,580 (172)

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, Volume 13, Issue 53, 24 September 2026.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source

Degenerative mitral valve regurgitation: best practice revolution [PDF]

, 2017
Degenerative mitral valve disease often leads to leaflet prolapse due to chordal elongation or rupture, and resulting in mitral valve regurgitation. Guideline referral for surgical intervention centres primarily on symptoms and ventricular dysfunction ...
Adams, David H., Falk, Volkmar, Rosenhek, Raphael   +2 more
core  

Mitral Annular Calcification: Understanding the Disease and Treatment Options

Structural Heart
Mitral annular calcification (MAC) is a degenerative process that causes calcium deposits along the mitral annulus. The pathophysiological mechanisms contributing to the development of MAC are not fully understood.
Marina Urena, MD, PhD, John Kikoïne, MD, Mayra Guerrero, MD   +2 more
doaj   +1 more source

Association of Transition Zone Burden With Recurrence in Elderly Patients With Paroxysmal Atrial Fibrillation Without Low‐Voltage Areas

Clinical Cardiology, Volume 49, Issue 9, September 2026.
Transition zone (TZ) is defined as regions with bipolar voltage between 0.5 and 1 mV in left atrium. In 158 elderly PAF patients without low‐voltage areas (LVA), TZ burden is associated with reduced left atrial conduction velocity (LACV) and independently predicts atrial tachyarrhythmia (ATA) recurrence following CPVI.
Yuxuan Wang, Yue Qiu, Haojun Wang, Chang Cui, Zidun Wang, Xiaohong Jiang, Mingfang Li, Juejin Wang, Hongwu Chen, Minglong Chen   +9 more
wiley   +1 more source

Long-term outcome of isolated mitral valve repair versus replacement for degenerative mitral regurgitation in propensity-matched patients

Objective This study was performed to investigate the long-term outcomes in patients with degenerative mitral regurgitation (MR) undergoing mitral valve repair (MVr) versus mitral valve replacement (MVR) without concomitant surgeries.
Skarsgard, P, Yong, MS, Peng, D, Kakuta, T, Cook, R, Ye, J   +5 more
core   +1 more source

The Systolic Anterior Motion After Mitral Valve Repair: A Narrative Review of Current Therapeutic Algorithms in the Operating Room

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Systolic anterior motion (SAM) represents the displacement of the anterior mitral leaflet during ventricular systole toward the interventricular septum, causing an obstruction of the outflow tract. Most of the published data regards the primary SAM that is associated with hypertrophic cardiomyopathy. This review was focused
Carmen Elena Opris, Horatiu Suciu, Catalin‐Constantin Badiu, Cosmin Ioan Opris, Alina Gabriela Negru, Simona Gurzu   +5 more
wiley   +1 more source

Clinical and Pathological Features of Degenerative Mitral Valve Disease: Billowing Mitral Leaflet Versus Fibroelastic Deficiency [PDF]

, 2014
Nagasaki University (長崎大学)博士(医学)Purpose: Degenerative mitral valve disease is distinguished with billowing mitral leaflet (BML) or fibroelastic deficiency (FED).
松丸, 一朗
core   +2 more sources

PREDICTION OF BLOOD FLOW VELOCITY AND LEAFLET DEFORMATION VIA 2D MITRAL VALVE MODEL [PDF]

Journal of Mechanical Engineering and Sciences, 2012
In the mitral valve, regional variations in structure and material properties combine to affect the biomechanics of the entire valve. From previous studies, we know that the mitral valve leaflet tissue is highly extensible. A two-dimensional model of the
M.A.H. Mohd Adib, N.H. Mohd Hasni, K. Osman, O. Maskon, K. Kadirgama   +4 more
doaj  

Preoperative left ventricular function in degenerative mitral valve disease

, 2014
AIM: The aim of the study is to determine the impact of the underlying etiology (Barlow's disease or fibroelastic deficiency) on left ventricular function in patients with degenerative mitral valve disease and severe mitral regurgitation.
Eduard Malev (598854)
core   +1 more source

Emerging Technologies for Percutaneous Mitral Valve Repair

Frontiers in Cardiovascular Medicine, 2019
Mitral regurgitation (MR) is a common disease affecting more than 4 million people in the United States and the European Union. A significant number of percutaneous valves have been developed recently, specifically designed for the mitral anatomy, and ...
Antonio Mangieri, Alessandra Laricchia, Francesco Giannini, Francesco Gallo, Faraj Kargoli, Annamaria Ladanyi, Annamaria Ladanyi, Luca Testa, Antonio Colombo, Azeem Latib, Azeem Latib   +10 more
doaj   +1 more source