Clinical observation on acupoint massage plus Vitalstim electrical stimulation for deglutition disorder after stroke [PDF]
, 2020 Li Tian +4 more
openalex +1 more source
Autism Research, EarlyView.ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by social communication deficits, repetitive behaviors, and sensory abnormalities. Sodium valproate (VPA) exposure during embryonic development is a well‐established preclinical model for ASD, leading to increased oxidative stress in the developing brain, including ...
Karla C. M. Costa +13 more
wiley +1 more source
A Novel Three-Dimensional Analysis of Tongue Movement During Water and Saliva Deglutition: A Preliminary Study on Swallowing Patterns [PDF]
, 2018 Giannina Álvarez +4 more
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić +4 more
wiley +1 more source
Gingival hyperplasia around dental implants in jaws reconstructed with free vascularized flaps: a case report series [PDF]
, 2018 Free vascularized flaps are the gold standard for reconstruction of the facial skeleton after surgical ablation of pathologies or when important atrophy of the jaws exists.
Brauner, E. +8 more
core
AZD0449, an inhaled JAK1 inhibitor, in healthy participants and patients with mild asthma
British Journal of Clinical Pharmacology, EarlyView.Aims Inhaled corticosteroids (ICS) plus bronchodilator are recommended for the treatment of asthma. Targeting the JAK1‐dependent pathway may be an alternative for asthma management in patients with incomplete response to ICS. The aim of this study was to investigate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD0449, a
Anna Lundahl +11 more
wiley +1 more source
Nutrition risk in age-related residential care : prevalence and associated factors in adults of advanced age : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutrition and Dietetics, Massey University, Albany, New Zealand [PDF]
, 2017 Background: The New Zealand population is rapidly ageing. Adults of advanced age (≥85 years) are one of the fastest growing population groups with numbers expected to double by 2036.
Senior, Stacey Marie
core
British Journal of Clinical Pharmacology, EarlyView.Aim Cannabis‐based medicines are gaining interest and being explored for new therapeutic indications, many of which commonly affect older medical patients. As most previous studies of the population pharmacokinetics of cannabinoids have been performed in healthy adults, this study aimed to investigate the population pharmacokinetics of Δ9 ...
Ida Klitzing Storgaard +12 more
wiley +1 more source
Development of a Physiologically Based Pharmacokinetic (PBPK) Simulation Model for Nicotine
Biopharmaceutics &Drug Disposition, EarlyView.This study developed a region‐specific PBPK model for nicotine integrating various administration routes and lung compartments, validated using clinical PK data. This model enables an accurate prediction of nicotine kinetics and supports dose optimization for safer nicotine delivery systems. ABSTRACT Tobacco is a major cause of chronic diseases such as
Brian Kim +8 more
wiley +1 more source