Results 181 to 190 of about 22,932 (328)

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

open access: yesExploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li   +6 more
wiley   +1 more source

Autophagy‐Targeting Nanomedicine: Strike at the Heart of the Cancer via Precise Modulation of Autophagy

open access: yesExploration, EarlyView.
This review emphasizes the critical role of autophagy in cancer treatment, highlighting the development of autophagy‐targeting nanomedicines and their applications in combination therapies. It explores how nanoplatforms can effectively regulate autophagy, underscoring the potential of integrating autophagy modulation with other treatment strategies to ...
Zhouyi Sun   +10 more
wiley   +1 more source

Sarcopenia Trajectories Predict Survival in Operable Head and Neck Cancer

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Sarcopenia is associated with increased treatment toxicity and survival in head and neck squamous cell cancer (HNSCC). This study evaluates sarcopenia trajectories and their association with overall survival (OS) and disease‐free survival (DFS) in operable HNSCC.
Marco A. Mascarella   +12 more
wiley   +1 more source

Health‐Related Quality of Life in Patients With a Head and Neck Sarcoma: A Mixed‐Methods Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Patients with head and neck sarcomas (HNS) face unique health‐related quality of life (HRQoL) challenges due to its disease rarity. This study examined and identified the prevalence of generic‐ and location‐specific HRQoL issues.
E. Koffi   +25 more
wiley   +1 more source

Prophylactic Versus Reactive (PvR) Feeding in Patients Undergoing (Chemo)radiation in Head and Neck Cancers: Results of a Phase III Randomized Controlled Trial

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Optimal feeding strategy (Prophylactic vs. Reactive) during Radiation Therapy (RT) for Head and Neck Cancers (HNC) remains to be established. Methods This phase III trial randomized (1:1) patients of HNC to prophylactic [nasogastric tube (NGT) placed at least 1 day before RT starting] versus reactive arm (NGT when required).
Sarbani Ghosh Laskar   +21 more
wiley   +1 more source

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