Results 91 to 100 of about 149 (146)

Hedgehogs and Angiostrongylus cantonensis: Uncovering the Role of Atelerix albiventris in the Parasite Life Cycle

Integrative Zoology, EarlyView.
ABSTRACT The ongoing invasion of the zoonotic parasite Angiostrongylus cantonensis threatens humans, other mammals, and birds. In Mallorca, neurological disorders associated with this parasite are increasingly reported in free‐living Algerian hedgehogs, Atelerix algirus, raising public health concerns.
Anna Šipková, Kristýna Javorská, Lucia Anettová, Divakaran Pandian, Petr Cibulka, Jana Kačmaříková, Ladislav Novotný, David Modrý   +7 more
wiley   +1 more source

Reduction of DNA Topoisomerase Top2 Reprograms the Epigenetic Landscape and Extends Health and Life Span Across Species

Aging Cell, EarlyView.
This study demonstrates that reducing the enzyme topoisomerase Top2 or its mammalian homolog TOP2B promotes longevity across multiple species, including yeast, worms, and mice. At the cellular/molecular level, TOP2B reduction mitigates the major cellular aging hallmarks such as epigenetic alterations, cell senescence, lysosomal biogenesis, and ...
Man Zhu, Meng Ma, Lunan Luo, Feiyang Li, Jiashun Zheng, Yan Pan, Lu Yang, Ying Xiao, Ziyan Wang, Bo Xian, Yi Zheng, Hao Li, Jing Yang   +12 more
wiley   +1 more source

Ambulatory devices to detect sleep bruxism: a narrative review

Australian Dental Journal, Volume 69, Issue S1, Page S53-S62, June 2024.
Abstract Sleep bruxism is a masticatory muscle activity that occurs during sleep and presents as rhythmic or non‐rhythmic activities commonly seen in healthy individuals but might also represent movement or sleep disorders. Given that the clinical presentations of sleep bruxism are relevant to dentistry, the early detection of sleep bruxism is of ...
C Li, S Yap, A Loh, YJ Yap, O Kujan, R Balasubramaniam   +5 more
wiley   +1 more source

IFNγ Signaling Impairs Regulatory B Cell Function Resulting in Worse Control of Esophageal Food Allergy

Allergy, EarlyView.
We used patient samples and a murine model to understand the contribution of Bregs to EoE immunopathology. We find that Breg‐derived IL‐10 is important for controlling EoE, but that Breg expansion and function are impaired in this condition. We identify IFNγ as a key negative regulator of Breg function in mice and patients with EoE. Bregs, regulatory B
Rachel L. Clement, Julie Dilollo, Eric M. Rodríguez‐López, Cleandre M. Guerrier, David A. Hill   +4 more
wiley   +1 more source

Impact of honey on post‐tonsillectomy pain in children (BEE PAIN FREE Trial): a multicentre, double‐blind, randomised controlled trial*

Anaesthesia, EarlyView.
Summary Introduction Tonsillectomy, a common childhood surgery, is associated with difficult postoperative recovery. Previous reviews provided low‐grade evidence that honey may improve recovery. The BEE PAIN FREE study investigated whether honey alongside multimodal analgesia improved the recovery trajectory in children following tonsillectomy ...
David Sommerfield, Aine Sommerfield, Daisy Evans, Neil Hauser, Shyan Vijayasekaran, Paul Bumbak, Hayley Herbert, Cornelia Locher, Lee Yong Lim, R. Nazim Khan, Britta S. von Ungern‐Sternberg   +10 more
wiley   +1 more source

Uptake of orally administered tranexamic acid in women during active labor: A pilot intervention study on prophylactic treatment of postpartum hemorrhage

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Women in active labor given oral tranexamic acid do reach therapeutic plasma concentrations. Time to therapeutic concentration is longer compared with intravenous administration, but duration in the therapeutic interval is significantly longer. Abstract Introduction Postpartum hemorrhage is the leading cause of maternal mortality worldwide.
Gita Strindfors, Pelle G. Lindqvist, Margit Endler   +2 more
wiley   +1 more source

Children With Sydenham Chorea and Psychiatric Disorders Had Variable Long‐Term Outcomes and Required Multidisciplinary Management

Acta Paediatrica, Volume 114, Issue 6, Page 1437-1444, June 2025.
ABSTRACT Aim Sydenham chorea (SC) is a globally significant, post‐streptococcal, childhood neuropsychiatric condition that is rare in western Europe. This retrospective single‐centre study focused on children with neuropsychiatric features of SC. Methods Participants were recruited from neuropsychiatry referrals to a regional paediatric neurology ...
Nadine Mushet, Michael Morton, Helen Minnis, Christopher Gillberg   +3 more
wiley   +1 more source

Robin Sequence: From Dilemmas to Developing an Adaptable Standardized Stepwise Approach

Acta Paediatrica, EarlyView.
ABSTRACT Aim To review the literature to identify key issues causing variation in clinical practice, assess the knowledge gap, and develop a standardised pathway for managing upper airway obstruction (UAO) in infants with Robin sequence (RS). Methods The tripartite framework of evidence‐based practice, which included a systematic review of the ...
Dimple Goel, Andrew Wilson, Shripada Rao, David Gillett, H. Hayley Herbert, Anne O'Donnell   +5 more
wiley   +1 more source

Four‐Fold Increase of the Number of Children Diagnosed With Paediatric Feeding Disorder in Northern Sweden in 2012–2022

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to investigate the annual prevalence and characteristics of Paediatric Feeding Disorder (PFD) in Västerbotten county, Sweden, during the years 2012–2022. Methods In this retrospective study, medical records of patients attending paediatric clinics with possible feeding problems were identified by applying pre ...
Elsa Gustavsson, Martina Kölgran, Maria Jonsson, Kajsa Lamm, Anna Chmielewska   +4 more
wiley   +1 more source

Digital medication and patients' right of autonomy in Spain

Bioethics, Volume 39, Issue 5, Page 482-491, June 2025.
Abstract The progress the Internet has experienced in recent years has brought about huge changes and social transformation in all aspects of our lives. One such aspect greatly impacted has been our health, where we can talk about the existence of an ‘Internet of Medical Things’.
Salvador Pérez Álvarez
wiley   +1 more source