Results 161 to 170 of about 1,256,209 (244)
Breathe, Eat, Talk: Three Essential Ingredients to Quality‐of‐Life Outcomes in Movement Disorders
Movement Disorders Clinical Practice, EarlyView.Abstract Background Breathing, eating, and talking (BET) impairments are common yet frequently underrecognized features of movement disorders. Deficits in respiration, swallowing, voice, and speech may emerge early in the course of a disease, adversely affecting safety, participation, and quality of life.
John Dean +16 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background Relatively little is known about voice and speech abnormalities and their changes after deep brain stimulation (DBS) in patients with dystonia. Objective The aim was to determine the incidence of speech abnormalities, including laryngeal dystonia, among patients with dystonia receiving DBS and to characterize their response to this ...
Ian O. Bledsoe +7 more
wiley +1 more source
Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review
Movement Disorders, EarlyView.Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska +6 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background Bilateral pallidal deep brain stimulation (GPi‐DBS) is effective for dystonia. Long‐term evolution of therapeutic benefit and emergence of parkinsonism have not been systematically characterized. Objectives To assess 15‐year dystonia outcomes and characterize parkinsonism after bilateral GPi‐DBS.
Clément Desjardins +51 more
wiley +1 more source
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose To develop, optimize, and characterize a respiratory motion‐resolved free‐running isotropic 3D carotid vessel wall T1 mapping technique named CARISMAT1C. Methods An inversion‐recovery gradient‐echo free‐running pulse sequence with interleaved double flip‐angle (2FA) was implemented, and an extended‐phase‐graph dictionary was used to ...
Isabel Montón Quesada +7 more
wiley +1 more source
Muscle &Nerve, EarlyView.ABSTRACT Congenital myasthenic syndromes (CMS) are inherited disorders caused by mutations in genes encoding proteins essential for neuromuscular junction (NMJ) function. Pathogenic variants have been identified in more than 35 genes, underscoring the complexity of synaptic biology and the wide range of mechanisms that can compromise neuromuscular ...
Rocio‐Nur Villar‐Quiles +5 more
wiley +1 more source
Treatment Preferences of Patients With Myasthenia Gravis: A Qualitative Study
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims The burden of myasthenia gravis (MG) is often underestimated, and studies usually focus on the symptom burden. However, treatment‐related adverse events also contribute to patients' burdens and affect their treatment decisions.
Meg Mendoza +6 more
wiley +1 more source
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims Data on respiratory status and care in older adults with Duchenne muscular dystrophy (DMD) remain limited. This study aimed to characterize respiratory status, respiratory physiotherapy, and associated clinical features in patients with DMD aged ≥ 30 years.
Keisuke Yorimoto +7 more
wiley +1 more source
Emergencies in Amyotrophic Lateral Sclerosis
Muscle &Nerve, EarlyView.ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal +9 more
wiley +1 more source