Results 201 to 210 of about 1,332,430 (297)

Multimodal Magnetic Resonance Imaging and Machine Learning Uncovers Distinct Progression Patterns in Friedreich Ataxia

open access: yesMovement Disorders, EarlyView.
Abstract Background Friedreich ataxia (FRDA) is a rare neurodegenerative disorder with heterogenous clinical progression, complicating prognosis and trial design. Neuroimaging offers objective biomarkers of disease progression, yet variability in progression patterns remains poorly understood.
Susmita Saha   +8 more
wiley   +1 more source

The Gut–Brain Axis in Parkinson's Disease: From Clinical Observation toward Mechanism‐Based Precision Medicine

open access: yesMovement Disorders, EarlyView.
Abstract Gastrointestinal dysfunction is increasingly recognized as a core feature of Parkinson's disease (PD), affecting quality of life, nutrition, medication response, and potentially the earliest stages of pathogenesis. This perspective traces the evolution of the gut from a neglected source of non‐motor symptoms to a central component of ...
Filip Scheperjans   +4 more
wiley   +1 more source

Respiratory‐Resolved Isotropic 3D T1 Mapping of the Carotid Vessel Wall With B1+ Correction (CARISMAT1C)

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop, optimize, and characterize a respiratory motion‐resolved free‐running isotropic 3D carotid vessel wall T1 mapping technique named CARISMAT1C. Methods An inversion‐recovery gradient‐echo free‐running pulse sequence with interleaved double flip‐angle (2FA) was implemented, and an extended‐phase‐graph dictionary was used to ...
Isabel Montón Quesada   +7 more
wiley   +1 more source

Oropharyngeal dysphagia and amyloid beta pathology in the TgF344-AD rat model of Alzheimer's disease. [PDF]

open access: yesFront Behav Neurosci
Cullins MJ   +7 more
europepmc   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal   +9 more
wiley   +1 more source

Incidence of unplanned gastrostomy tube replacements and associated complications in people with motor neurone disease and other conditions: A retrospective audit of an Australian dietitian‐led clinic

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Gastrostomy tube placement is a common intervention for long‐term nutrition in people with dysphagia. Minimising complications such as tube dislodgement is integral in gastrostomy management, as unplanned replacements may require urgent care to prevent stoma closure.
Emily Farrugia   +6 more
wiley   +1 more source

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