Results 21 to 30 of about 149 (146)

Effect of Intraoperative Posture on Accurate Diagnostic Rate of Intraoperative Nerve Monitoring During Esophagectomy

Annals of Gastroenterological Surgery, EarlyView.
Adequate contact between the intubation tube and the vocal cord muscles is crucial for effective intraoperative nerve monitoring use during esophagectomy. Additionally, intraoperative posture significantly affects diagnostic outcomes and should be carefully considered.
Masami Yuda, Keita Takahashi, Yoshitaka Ishikawa, Takanori Kurogochi, Akira Matsumoto, Naoko Fukushima, Takahiro Masuda, Naoto Takahashi, Fumiaki Yano, Ken Eto   +9 more
wiley   +1 more source

Detecting the Difficult: An Intronic NPC1 Variant Hiding in Plain Sight

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT An illustration of the importance of manual data review for identifying rare intronic variants adjacent to homopolymers is presented here. A 14‐year‐old male with Niemann‐Pick Type C disease confirmed biochemically was only found to have a heterozygous pathogenic variant by molecular analysis. A manual review of the Next Generation Sequencing (
Caroline Gully Brown, Matthew Bower, Matthew Schomaker, Jessica Goldstein, Jeanine Jarnes, Chester B. Whitley, Nishitha R. Pillai   +6 more
wiley   +1 more source

Gut Microbiome Pilot Study of Patients With CHARGE Syndrome and Sibling Controls

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Difficulties with feeding and digestion are common in individuals with CHARGE syndrome. Animal models with CHD7 gene variants demonstrate abnormal gut innovation and dysmotility. Our pilot study evaluated whether individuals with CHARGE syndrome have differences in their gut microbiome compared to unaffected siblings.
Emily R. Chedrawe, Jessica Connors, Angela Arra, Katherine Dunn, Kim Blake, Johan van Limbergen   +5 more
wiley   +1 more source

Identifying the optimal dose of cannabidiol by intrabuccal administration in Kramnik (C3HeB/FeJ) mice

Animal Models and Experimental Medicine, EarlyView.
Cannabidiol (CBD) has numerous therapeutic properties, and is used to treat neurological conditions, such as neuroinflammation. However, the optimal dose of CBD to penetrate the brain requires further investigation. The primary aim of this study was to use a mouse model and the intrabuccal route for CBD administration to determine the optimal dose at ...
Oluwadara Pelumi Omotayo, Siyethemba Bhengu, Kobus Venter, Yolandy Lemmer, Shayne Mason   +4 more
wiley   +1 more source

Early life functional transitions impact craniofacial morphology in osteogenesis imperfecta

The Anatomical Record, EarlyView.
Abstract Early life behaviors have a profound role in shaping adult craniofacial morphology. During early life, all mammals undergo the dynamic transition from suckling to mastication, a period coinciding with rapid cranial biomineralization. Osteogenesis imperfecta (OI), a genetic disorder that impacts the production of type I collagen, disrupts ...
Courtney A. Miller, Tanusha Emanuel, Rachel A. Menegaz   +2 more
wiley   +1 more source

PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential

Cytoskeleton, EarlyView.
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah, Franz Meitinger, Midori Ohta   +2 more
wiley   +1 more source

Development and Preliminary Validation of a Self‐Report Measure of Sensory and Moral Disgust Toward Perceived Unhealthy Food

International Journal of Eating Disorders, EarlyView.
ABSTRACT Background Disgust toward perceived unhealthy food has been largely overlooked in understanding the development and persistence of disordered eating, partly due to a lack of measurement tools. To address this gap, we developed new measures of disgust toward perceived unhealthy food. Method We evaluated the psychometric properties of a new self‐
Niyati Mistry, Corinna M. Elliott, Nassim Tabri   +2 more
wiley   +1 more source

Relationship Between Gluten Structural Properties and Noodle Texture: Insights From Seven Wheat Varieties

Food Bioengineering, EarlyView.
Noodle quality differences among seven wheat varieties were evaluated through integrated sensory and textural analyses, revealing a significant correlation with gluten structure properties. ABSTRACT A comprehensive understanding of how gluten properties affect noodle texture remains limited.
Rui Chen, Yiqing Zhu, Luman Sang, Liangxing Zhao, Sameh Sharafeldin, Li Zhi, Chongyi Wu, Qingyu Zhao, Qun Shen   +8 more
wiley   +1 more source

Exploring the application of ferroelectret nanogenerators in medical engineering

FlexMat, EarlyView.
Abstract Flexible devices derived from piezoelectric materials have gained considerable attention due to their exceptional biocompatibility. Among these, ferroelectret nanogenerators (FENG) is a novel type of flexible piezoelectric device that integrates self‐powering, actuation, and sensing capabilities.
Xianfa Cai, Xiaowen Han, Jiaqi Xie, Yunqi Cao, Wei Li   +4 more
wiley   +1 more source

Tracheoesophageal Voicing Following Resistance‐Based Dysphagia Rehabilitation: An Exploratory Multidimensional Assessment

Head &Neck, EarlyView.
ABSTRACT Background This exploratory study investigated tracheoesophageal voicing following 6 weeks of resistance‐based dysphagia rehabilitation with the SEA2.0, using a multidimensional assessment approach. Methods Twenty laryngectomized participants were assessed at T0 (baseline), T1 (after 6 weeks training), and T2 (after 8 weeks rest).
Marise Neijman, Klaske E. van Sluis, Rob J. J. H. van Son, Martijn M. Stuiver, Frans J. M. Hilgers, Michiel W. M. van den Brekel, Maarten J. A. van Alphen, Lisette van der Molen   +7 more
wiley   +1 more source