Results 131 to 140 of about 795,358 (310)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Degradation products formed during UV-irradiation of humic waters [PDF]

, 1996
Natural humic lake water and aqueous solutions of humic substances were treated with ultraviolet (UV) radiation (λ = 254 nm). The effects on the dissolved organic carbon content (DOC) and the absorbance at 254 nm (Abs254) and 460 nm (Abs460) were ...
Peter Backlund2 and Maaret Kulovaara, Nina Corin1   +1 more
core  

Degradation Product of Glucuronamide

YAKUGAKU ZASSHI, 1962
Y, NITTA, J, IDE, N, OGIKUBO
openaire   +3 more sources

Liquid chromatography of dibutyldithiocarbamate degradation products [PDF]

Journal of Chromatography A, 1984
Brandsteterova, E., Lehotay, J., Garaj, J., Leclercq, P.A.   +3 more
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

ANTILEISHMANIAL EPIDIOXYSTEROLS FROM THE COLOMBIAN MARINE SPONGE Ircinia campana ARE OXIDATION PRODUCTS FROM NATURALLY OCCURRING Δ5,7 STEROLS LOS EPIDIOXIESTEROLES CON ACTIVIDAD ANTILEISHMANIA DE LA ESPONJA MARINA COLOMBIANA Ircinia campana SON PRODUCTOS DE OXIDACIÓN DE LOS ESTEROLES NATURALES Δ5,7

Vitae, 2007
Marine sponges of the genus Ircinia are known to contain several classes of metabolites, some of them with interesting biological activities as furanesesterterpenes, polyprenylated hydroquinones, macrolides, sulfur containing terpenoids, and steroids ...
Diana M. MÁRQUEZ F., Alejandro MARTÍNEZ M.   +1 more
doaj  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Identification of methomyl photocatalytic degradation products [PDF]

, 2016
Photocatalytic degradation of the methomyl pesticide in aqueous suspension of TiO2 using an Osram ultra-vitalux® lamp (315-400 nm) was investigated. The effect of parameters such as initial concentration of catalyst, initial methomyl concentration ...
Tolić, Ljiljana, Marinković, Aleksandar, Tomašević, Anđelka, Laušević, Mila, Mijin, Dušan, Radišić, Marina   +5 more
core  

Study on the Degradation Products of Zearalenone Using UHPLC-Q-TOF-MS

Liang you shipin ke-ji
The study employed UHPLC-Q-TOF-MS to analyze zearalenone (ZEN) in maize processed by high-temperature and high-pressure extrusion. The degradation efficiency and degradation products were investigated.
REN Ling-yun, YANG Lin-lin, JIANG Yuan-yuan, DONG Bin, WANG Jun, XUE Xia, WANG Fei-fei, ZHANG Jin-na   +7 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source