Results 61 to 70 of about 795,358 (310)
Plasticiser loss from plastic or rubber products through diffusion and evaporation [PDF]
, 2019 Polymers experience degradation during storage and service. One of the main degradation mechanisms of plasticised-polymer products is the loss of plasticiser, which leads to poorer mechanical properties and eventual contamination of the surrounding ...
Hedenqvist, Mikael S., +2 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Pharmaceutical Sciences, 2016 Background: Edoxaban is an orally active direct factor Xa inhibitor. The aim of the present study was to develop a stability indicating HPLC method for the quantification of edoxaban in bulk and in tablet dosage form. Methods: Edoxaban was separated on
Pasam Satyanarayana Reddy , V. Shanmukha Kumar Jagarlapudi, Chandra Bala Sekaran
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Characterisation of the mechanical and thermal degradation behaviour of natural fibres for lightweight automotive applications [PDF]
, 2013 It is well established that light-weighting of automotive parts leads to reduced carbon emissions over vehicle lifetime. Mineral fibres and fillers have a relatively high density and may require high levels of energy in their production, resulting in a ...
Liggat, John +3 more
core
Nanoclay effects on the degradation process and product patterns of polylactide [PDF]
, 2012 The addition of montmorillonite (MMT) nanoclays shifted the degradation product patterns of polylactide towards shorter lactic acid oligomers as compared to the product patterns of plain polylactide and halloysite modified polylactide hydrolysed under ...
Hakkarainen, Minna, +2 more
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Forced degradation study of torasemide: Characterization of its degradation products [PDF]
, 2013 Torasemide was subjected to forced degradation studies. Stress conditions were varied concerning hydrolysis (acid, base, and neutral), oxidation, photolysis, and thermal degradation in order to identify the potential degradation products and consequently
Živanović, Ljiljana +6 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source