Results 61 to 70 of about 7,724 (236)

A novel permanent magnet flux switching machine with an outer-rotor configuration for in-wheel light traction applications [PDF]

, 2012
This paper proposes a novel permanent magnet flux switching (PMFS) machine with an outer-rotor configuration for in-wheel light traction applications.
Shen, Jian-Xin, Wang, Yu, Luk, Patrick Chi-Kwong, Fei, Wei-Zhong, Jin, Meng-Jia   +4 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Instantons in 4-dimensional gauged O(5) Skyrme models [PDF]

, 2001
We consider a family of four-dimensional non-linear sigma models based on an O(5) symmetric group, whose fields take their values on the 4-sphere S4. An SO(4)-subgroup of the model is gauged.
Y. Brihaye, B. M. A. G. Piette, Brihaye, Y., Paturyan, V., V. Paturyan, Tchrakian, D.H., Piette, B.M.A.G., D. H. Tchrakian   +7 more
core   +1 more source

Workplace violence: A complex challenge demanding a systemic response

Scandinavian Journal of Work, Environment & Health
Workplace violence is associated with negative consequences for workers, organizations, and society. Experiencing violence at work has consistently been associated with an increased risk of symptoms of depression and anxiety, diagnosis of post-traumatic ...
Sofie Jaspers, Iben Karlsen, Birgit Aust
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Modelling and monitoring of resin transfer moulding [PDF]

, 2000
Modelling and monitoring tools appropriate for the resin transfer moulding composites manufacturing route were developed in this study. A simulation of the curing stage of the process based on a finite elements solution of the non-linear heat ...
Skordos, A.A., Skordos, Alexandros A.
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Modeling of Thermoplastic Composite Filament Winding

, 2000
Thermoplastic composite filament winding is an on-line consolidation process, where the composite experiences a complex temperature history and undergoes a number of temperature history affected microstructural changes that influence the structure's ...
Song, Xiaolan
core