Results 201 to 210 of about 7,058,514 (292)

Effectiveness of Bachmann's Bundle Pacing in a Patient With Severe Heart Failure and Refractory Atrial Fibrillation. [PDF]

J Arrhythm
Murase Y, Ogawa Y, Imai H, Mamiya K, Kawaguchi K.   +4 more
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Sensory Denervation Delays Burn Wound Healing in Experimental Second- and Third-Degree Burns: A Histopathological Rat Study. [PDF]

Eur Burn J
Horoz U, Ozakpinar HR, Inozu E, Seven E, Eryilmaz AT, Umudum H, Akturk UD, Tellioglu AT.   +7 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Forecasting of infectious disease epidemics in sexual networks using attenuated renewal processes. [PDF]

PLoS Comput Biol
Green WD, Overton CE, Ward T, McCarthy CV, Funk S.   +4 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Field and Laboratory Studies for Predicting Annual Generations of <i>Spodoptera littoralis</i> (Boisd.) Using Sex Pheromone Traps and Cumulative Heat Unit Measurements in Egypt. [PDF]

Insects
Ahmed AMM, Andrade-Yucailla V, Allam EAY, Saad MAA, Manaa SH, Dahi HF, Yones MS, Alcocer-Quishpe F, Barros-Rodríguez M.   +8 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Health Literacy and Tobacco Use: A Cross-Sectional Study of Associations Among Predominantly Low-Income Adults Motivated to Quit Smoking. [PDF]

Healthcare (Basel)
Rueden H, Kelley B, Douglas B, Mason L, Nattamai Subramanian Rajkumar J, Raol P, Spears CA.   +6 more
europepmc   +1 more source