Results 121 to 130 of about 1,407,971 (258)
Dissecting the Opposing Roles of Thermal Intensity and Growing Degree Days in Regulating Spring Wheat Protein Content. [PDF]
Lei X +13 more
europepmc +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Effects of climate and potential policy changes on heating degree days in current heating areas of China. [PDF]
Shi Y, Wang G, Gao X, Xu Y.
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
When Heat Meets Pollutants: Integrating Degree-Days and Chemical Activity Concepts for the Assessment of Temperature-Driven Toxicity. [PDF]
Gorokhova E +7 more
europepmc +1 more source
Generic calibration of a simple model of diurnal temperature variations for spatial analysis of accumulated degree-days. [PDF]
Felber R, Stoeckli S, Calanca P.
europepmc +1 more source
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Predicting the Onset Date of Cucumber Powdery Mildew Based on Growing Degree Days and Leaf Wetness Duration in Greenhouse Environment. [PDF]
Son M +10 more
europepmc +1 more source

